ArticleAmerican journal of epidemiology2019
Invited Commentary: Examining Sex/Gender Differences in Risk of Alzheimer Disease and Related Dementias-Challenges and Future Directions.
Article in American journal of epidemiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
31 citing papers in PubMed, 49 citations in OpenAlex.
- Sex differences in cognitive resilience in preclinical autosomal-dominant Alzheimer's disease carriers and non-carriers: Baseline findings from the API ADAD Colombia Trial.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2022Trial
- Association of glycolipid metabolism 6 factors index with cardiovascular and metabolic diseases, and its predictive value in disease progression.BMC endocrine disorders · 2026Article
- Three maxims for countering sex essentialism in scientific research.Biology of sex differences · 2025Review
- Intimate partner violence and cognitive functioning - toward quantifying dementia risk.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Sex/gender differences in lifetime dementia risk among Asian American and White older adults.NPJ dementia · 2025Article
- A health-equity framework for tailoring digital non-pharmacological interventions in aging.Nature. Mental health · 2024Article
- Sex and gender differences in cognitive resilience to aging and Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Review
- Systematic Review of Longitudinal Evidence and Methodologies for Research on Neighborhood Characteristics and Brain Health.Public health reviews · 2024Review
- Body Mass Index and Cognition: Associations Across Mid- to Late Life and Gender Differences.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023Article
- Sex and gender considerations in dementia: a call for global research.Nature aging · 2023Article
- Association of Age at Menopause and Hormone Therapy Use With Tau and β-Amyloid Positron Emission Tomography.JAMA neurology · 2023Article
- Sex- and age-specific impacts of smoking, overweight/obesity, hypertension, and diabetes mellitus in the development of disabling dementia in a Japanese population.Environmental health and preventive medicine · 2023Article
- Relationship between parental history of dementia, motor-cognitive and executive function performance in African American women.Journal of the neurological sciences · 2022Article
- Impact of Cerebral Amyloid Angiopathy in Two Transgenic Mouse Models of Cerebral β-Amyloidosis: A Neuropathological Study.International journal of molecular sciences · 2022Article
- Simple screening models for cognitive impairment in community settings: The IRIDE Cohort Study.Geriatrics & gerontology international · 2022Article
- How Selection Over Time Contributes to the Inconsistency of the Association Between Sex/Gender and Cognitive Decline Across Cognitive Aging Cohorts.American journal of epidemiology · 2022Article
- Sex is a defining feature of neuroimaging phenotypes in major brain disorders.Human brain mapping · 2022Review
- Prevalence and incidence of young onset dementia and associations with comorbidities: A study of data from the French national health data system.PLoS medicine · 2021Article
- Evaluation of Selective Survival and Sex/Gender Differences in Dementia Incidence Using a Simulation Model.JAMA network open · 2021Article
- Association of work-family experience with mid- and late-life memory decline in US women.Neurology · 2020Article
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1 author at 1 institution in 1 country.
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Abstract
The majority of people living with Alzheimer disease (AD) and related dementias are women. Longer life expectancy is one factor thought to contribute to this observation, but possible sex-specific biological mechanisms have received considerable attention from the research community. In the current issue of the Journal, Buckley et al. (Am J Epidemiol. 2019;188(7):1213-1223) use death certificate information on all deaths occurring among adults aged ≥60 years in Australia between 2006 and 2014 to evaluate sex/gender differences in rates of death with dementia (all types), AD dementia, and vascular dementia listed on the death certificate. The paper by Buckley et al. highlights several important methodological challenges for research examining sex/gender differences in risk of AD and related dementias, including challenges in measurement, survival bias and competing risks, and selection bias arising from sample selection. The current evidence on possible sex-specific biological risk factors for AD is intriguing, but there are numerous alternative explanations for differences in AD dementia and AD biomarkers between women and men. Triangulation of evidence from study designs with different strengths and weaknesses and transdisciplinary collaboration will be vital to generating conclusive evidence about sex/gender differences in risk of AD and related dementias.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.