Evidence map›Paper›PMID 30824808›Full record

Trial reportScientific reports2019

Glycemic control and survival in peritoneal dialysis patients with diabetes: A 2-year nationwide cohort study.

Masanori Abe, Takayuki Hamano, Junichi Hoshino, Atsushi Wada, Shigeru Nakai, Ikuto Masakane

Open access · goldAbstract readClinical TrialMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Observational
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Masanori AbeThe Committee of Renal Data Registry, Japanese Society for Dialysis Therapy, Tokyo, Japan. abe.masanori@nihon-u.ac.jp.ORCID 0000-0002-9156-5415
Takayuki HamanoThe Committee of Renal Data Registry, Japanese Society for Dialysis Therapy, Tokyo, Japan.
Junichi HoshinoThe Committee of Renal Data Registry, Japanese Society for Dialysis Therapy, Tokyo, Japan.ORCID 0000-0002-0444-101X
Atsushi WadaThe Committee of Renal Data Registry, Japanese Society for Dialysis Therapy, Tokyo, Japan.
Shigeru NakaiThe Committee of Renal Data Registry, Japanese Society for Dialysis Therapy, Tokyo, Japan.
Ikuto MasakaneThe Committee of Renal Data Registry, Japanese Society for Dialysis Therapy, Tokyo, Japan.
Japanese Society for Dialysis Therapy · JPFujita Health University · JPNihon University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

For glycemic control in patients with diabetes on peritoneal dialysis (PD), the level of glycated albumin (GA) associated with mortality is unclear. Accordingly, we examined the difference in the association of GA and glycated hemoglobin (HbA1c) with 2-year mortality in a Japanese Society for Dialysis Therapy cohort. We examined 1601 patients with prevalent diabetes who were on PD. Of these, 1282 had HbA1c (HbA1c cohort) and 725 had GA (GA cohort) measured. We followed them for 2 years from 2013 to 2015 and used Cox regression to calculate adjusted hazard ratios (HRs) and 95% confidence intervals (CIs) for 2-year mortality after adjusting for potential confounders in each cohort. No significant association was found between HbA1c levels and all-cause death HRs before and after adjustment for confounders in the HbA1c cohort. In contrast, the adjusted all-cause death HRs and 95% CIs for GAs < 12.0%, 12.0-13.9%, 16.0-17.9%, 18.0-19.9%, 20.0-21.9%, and ≥22.0%, compared with 14.0-15.9% (reference), were 1.56 (0.32-7.45), 1.24 (0.32-4.83), 1.32 (0.36-4.77), 2.02 (0.54-7.53), 4.36 (1.10-17.0), and 4.10 (1.20-14.0), respectively. In the GA cohort, GA ≥ 20.0% was significantly associated with a higher death HR compared with the reference GA. Thus, GA ≥ 20.0% appears to be associated with a decrease in survival in diabetic patients on PD. There were no associations between HbA1c levels and 2-year mortality in PD patients.

Indexed as

Diabetes MellitusPeritoneal DialysisRegistriesAgedDisease-Free SurvivalFemaleGlycated HemoglobinGlycated Serum AlbuminGlycation End Products, AdvancedHumansMaleMiddle AgedRetrospective StudiesSerum AlbuminSurvival RateGlycated HemoglobinGlycated Serum AlbuminGlycation End Products, Advancedhemoglobin A1c protein, humanSerum Albumin

Identifiers

PMID30824808
PMCPMC6397316
OpenAlexW2920051178

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.