Evidence map›Paper›PMID 30824217›Full record

ArticleJournal of the American Medical Directors Association2019

Patterns of Opioid Use in the 12 Months Following Geriatric Fragility Fractures: A Population-Based Cohort Study.

Michael T Torchia, Jeffrey Munson, Tor D Tosteson, Anna N A Tosteson, Qianfei Wang, Christine M McDonough, Tamara S Morgan, Julie P W Bynum, John-Erik Bell

Abstract read
In one paragraph

Article in Journal of the American Medical Directors Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Long-term clinical and socio-economic outcomes following wrist fracture: a systematic review and meta-analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2022
    Pooled it
  2. Review
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  5. Article
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  8. Opioid use in older orthopedic rehabilitation inpatients: a retrospective study.European journal of physical and rehabilitation medicine · 2023
    Observational
  9. Review
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  11. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Michael T TorchiaDepartment of Orthopedics, Dartmouth-Hitchcock Medical Center, Lebanon, NH.
Jeffrey MunsonDepartment of Medicine, Geisel School of Medicine at Dartmouth, Lebanon, NH; The Dartmouth Institute for Health Policy and Clinical Practice, Geisel School of Medicine at Dartmouth, Lebanon, NH.
Tor D TostesonThe Dartmouth Institute for Health Policy and Clinical Practice, Geisel School of Medicine at Dartmouth, Lebanon, NH.
Anna N A TostesonDepartment of Medicine, Geisel School of Medicine at Dartmouth, Lebanon, NH; The Dartmouth Institute for Health Policy and Clinical Practice, Geisel School of Medicine at Dartmouth, Lebanon, NH; Department of Biomedical Data Science, Geisel School of Medicine at Dartmouth, Lebanon, NH.
Qianfei WangThe Dartmouth Institute for Health Policy and Clinical Practice, Geisel School of Medicine at Dartmouth, Lebanon, NH.
Christine M McDonoughDepartment of Physical Therapy, School of Rehabilitation Sciences, and Department of Orthopedic Surgery, School of Medicine, University of Pittsburgh, Pittsburgh, PA.
Tamara S MorganThe Dartmouth Institute for Health Policy and Clinical Practice, Geisel School of Medicine at Dartmouth, Lebanon, NH.
Julie P W BynumDepartment of Medicine, Geisel School of Medicine at Dartmouth, Lebanon, NH; The Dartmouth Institute for Health Policy and Clinical Practice, Geisel School of Medicine at Dartmouth, Lebanon, NH.
John-Erik BellDepartment of Orthopedics, Dartmouth-Hitchcock Medical Center, Lebanon, NH; The Dartmouth Institute for Health Policy and Clinical Practice, Geisel School of Medicine at Dartmouth, Lebanon, NH. Electronic address: john-erik.bell@hitchcock.org.

Funding

Prognostic Value of Lumbar Spine MRIP60AR048094 · NIAMS · DARTMOUTH COLLEGE · PI WEINSTEIN, JAMES N · 2003 to 2007
$6.2M
Outcomes Calculators for Informed Decision Making in Back SurgeryP60AR062799 · NIAMS · DARTMOUTH COLLEGE · PI TOSTESON, ANNA N. A. · 2012 to 2016
$6.1M
NIAMS NIH HHS P60 AR048094NIAMS NIH HHS P60 AR062799
6 · The paper itself

Abstract

objectivesFractures of the hip, distal radius, and proximal humerus are common in the Medicare population. This study's objective was to characterize patterns and duration of opioid use, including regional variations in use, after both surgical and nonoperative management.

designPopulation-based cohort study. SETTING AND

participantsA cohort of opioid-naïve community-dwelling US Medicare beneficiaries who survived a hip, distal radius, or proximal humerus fracture between January 1, 2007 and December 31, 2010. Cohort members were required to be opioid-naïve for 4 months prior to fracture. MEASURES: We analyzed the proportion of patients with an active opioid prescription in each month following the index fracture, and report continued fills at 12 months postfracture. We also compared opioid prescription use in fractures treated surgically and nonsurgically and characterized state-level variation in opioid prescription use at 3 months postfracture.

resultsThere were 91,749 patients included in the cohort. Hip fracture patients had the highest rate of opioid use at 12 months (6.4%), followed by proximal humerus (5.7%), and distal radius (3.7%). Patients who underwent surgical fixation of proximal humerus and wrist fractures had higher rates of opioid use in each of the first 12 postoperative months compared with those managed nonoperatively. There was significant variation of opioid use at the state level, ranging from 7.6% to 18.2% of fracture patients filling opioid prescriptions 3 months after the index fracture. CONCLUSIONS/IMPLICATIONS: Opioid-naïve patients sustaining fragility fractures of the hip, proximal humerus, or distal radius are at risk to remain on opioid medications 12 months after their index injury, and surgical management of proximal humerus and distal radius fractures increases opioid use in the 12 months after the index fracture. There is significant state-level variation in opiate consumption after index fracture in nonvertebral geriatric fragility fractures. Opportunity exists for targeted quality improvement efforts to reduce the variation in opioid use following common geriatric fragility fractures.

Indexed as

Drug UtilizationAgedAged, 80 and overAnalgesics, OpioidCohort StudiesFemaleHumansMaleOsteoporotic FracturesUnited StatesAnalgesics, OpioidFragility fracturenonoperative treatmentopioidssurgery

Identifiers

PMID30824217
PMCPMC6400293

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.