Evidence map›Paper›PMID 30823566›Full record

ReviewJournal of clinical medicine2019

Medication in AN: A Multidisciplinary Overview of Meta-Analyses and Systematic Reviews.

Corinne Blanchet, Sébastien Guillaume, Flora Bat-Pitault, Marie-Emilie Carles, Julia Clarke, Vincent Dodin, Philibert Duriez, Priscille Gerardin, Mouna Hanachi-Guidoum, Sylvain Iceta and 4 more

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. The Efficacy of Pharmacological Treatment of Depression in Anorexia Nervosa and Underweight Patients: A Systematic Review.European eating disorders review : the journal of the Eating Disorders Association · 2026
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Corinne BlanchetMaison de Solenn-Maison des Adolescents, Cochin Hospital, Assistance Publique-Hôpitaux de Paris, 75014 Paris, France. corinne.blanchet@aphp.fr.
Sébastien GuillaumeFrench Federation Anorexia Bulimia (FFAB), 75014 Paris, France. s-guillaume@chu-montpellier.fr.
Flora Bat-PitaultFrench Federation Anorexia Bulimia (FFAB), 75014 Paris, France. flora.bat@ap-hm.fr.
Marie-Emilie CarlesMaison de Solenn-Maison des Adolescents, Cochin Hospital, Assistance Publique-Hôpitaux de Paris, 75014 Paris, France. marie-emilie.carles@aphp.fr.
Julia ClarkeFrench Federation Anorexia Bulimia (FFAB), 75014 Paris, France. julia.clarke@aphp.fr.
Vincent DodinFrench Federation Anorexia Bulimia (FFAB), 75014 Paris, France. dodin.vincent@ghicl.net.
Philibert DuriezFrench Federation Anorexia Bulimia (FFAB), 75014 Paris, France. phduriez@gmail.com.ORCID 0000-0001-7321-6820
Priscille GerardinFrench Federation Anorexia Bulimia (FFAB), 75014 Paris, France. priscille.gerardin@chu-rouen.fr.
Mouna Hanachi-GuidoumFrench Federation Anorexia Bulimia (FFAB), 75014 Paris, France. mouna.hanachi@aphp.fr.ORCID 0000-0002-7228-8723
Sylvain IcetaFrench Federation Anorexia Bulimia (FFAB), 75014 Paris, France. sylvain.iceta@chu-lyon.fr.ORCID 0000-0002-0054-1865
Juliane LegerPediatric Endocrinology Diabetology Department, Reference Centre for Endocrine Growth and Development Diseases, Robert Debré University Hospital, Assistance Publique-Hôpitaux de Paris, 75019 Paris, France. juliane.leger@aphp.fr.
Bérénice SegrestinFrench Federation Anorexia Bulimia (FFAB), 75014 Paris, France. berenice.segrestin@chu-lyon.fr.
Chantal StheneurFrench Federation Anorexia Bulimia (FFAB), 75014 Paris, France. chantal.stheneur@fsef.net.
Nathalie GodartFrench Federation Anorexia Bulimia (FFAB), 75014 Paris, France. nathalie.godart@fsef.net.

Funding

French Federation Anorexia Bulimia 1
6 · The paper itself

Abstract

Drugs are widely prescribed for anorexia nervosa in the nutritional, somatic, and psychiatric fields. There is no systematic overview in the literature, which simultaneously covers all these types of medication. The main aims of this paper are (1) to offer clinicians an overview of the evidence-based data in the literature concerning the medication (psychotropic drugs and medication for somatic and nutritional complications) in the field of anorexia nervosa since the 1960s, (2) to draw practical conclusions for everyday practise and future research. Searches were performed on three online databases, namely MEDLINE, Epistemonikos and Web of Science. Papers published between September 2011 and January 2019 were considered. Evidence-based data were identified from meta-analyses, if there were none, from systematic reviews, and otherwise from trials (randomized or if not open-label studies). Evidence-based results are scarce. No psychotropic medication has proved efficacious in terms of weight gain, and there is only weak data suggesting it can alleviate certain psychiatric symptoms. Concerning nutritional and somatic conditions, while there is no specific, approved medication, it seems essential not to neglect the interest of innovative therapeutic strategies to treat multi-organic comorbidities. In the final section we discuss how to use these medications in the overall approach to the treatment of anorexia nervosa.

Indexed as

anorexia nervosacomorbiditycomplicationdrug-treatmentmedicationnutritionpharmacotherapy

Identifiers

PMID30823566
PMCPMC6406645

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.