Evidence map›Paper›PMID 30823523›Full record

ArticleMolecules (Basel, Switzerland)2019

Microwave-Assisted Extraction of Multiple Trace Levels of Intermediate Metabolites for Camptothecin Biosynthesis in Camptotheca acuminata and Their Simultaneous Determination by HPLC-LTQ-Orbitrap-MS/MS and HPLC-TSQ-MS.

Zhaoxia Jin, Ruyi Wan, Ruxue Yan, Yingying Su, Honglan Huang, Lihan Zi, Fang Yu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Zhaoxia JinSchool of Biological Engineering, Dalian Polytechnic University, Dalian 116034, China. jinzx@dlpu.edu.cn.
Ruyi WanSchool of Biological Engineering, Dalian Polytechnic University, Dalian 116034, China. shengwu5022016@163.com.
Ruxue YanSchool of Biological Engineering, Dalian Polytechnic University, Dalian 116034, China. swgc502@163.com.
Yingying SuSchool of Biological Engineering, Dalian Polytechnic University, Dalian 116034, China. cxsu2016@163.com.
Honglan HuangCollege of Basic Medical Sciences, Jilin University, Changchun 130021, China. shengwu501@126.com.
Lihan ZiSchool of Life Science and Biotechnology, Dalian University of Technology, Dalian 116024, China. lihanzi@dlut.edu.cn.
Fang YuSchool of Biological Engineering, Dalian Polytechnic University, Dalian 116034, China. fyu0506@gmail.com.
Dalian Polytechnic University · CNDalian University · CNJilin University · CN

Funding

National Natural Science Foundation of China 31670604 and 31570303Natural Science Foundation of Liaoning Province 20180550237
6 · The paper itself

Abstract

Camptothecin (CPT) has strong antitumor activity and is used as an anticancer therapeutic agent. To better understand and decipher the pathway of CPT biosynthesis in

Indexed as

Biosynthetic PathwaysCamptothecaCamptothecinChromatography, High Pressure LiquidMicrowavesMolecular StructureOrganic ChemicalsPlant ExtractsSolid Phase ExtractionSolventsTandem Mass SpectrometryCamptothecinOrganic ChemicalsPlant ExtractsSolventscamptothecinHPLC-LTQ-MS/MSmetabolitesmicrowave assisted extractionTaguchi experimental design

Identifiers

PMID30823523
PMCPMC6413206
OpenAlexW2917495835

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.