Evidence map›Paper›PMID 30823512›Full record

ReviewGels (Basel, Switzerland)2019

Calcium-Dependent RTX Domains in the Development of Protein Hydrogels.

Beyza Bulutoglu, Scott Banta

Abstract readReview
In one paragraph

Review in Gels (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Supramolecular assembly of multifunctional protein gels via anMolecular systems design & engineering · 2024
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Beyza BulutogluDepartment of Chemical Engineering, Columbia University, 500 W 120th Street, New York, NY 10027, USA. bbulutoglu@mgh.harvard.edu.ORCID 0000-0002-4435-413X
Scott BantaDepartment of Chemical Engineering, Columbia University, 500 W 120th Street, New York, NY 10027, USA. sbanta@columbia.edu.ORCID 0000-0001-7885-0150

Funding

Air Force Office of Scientific Research FA9550-12-1-0112National Science Foundation 1402656
6 · The paper itself

Abstract

The RTX domains found in some pathogenic proteins encode repetitive peptide sequences that reversibly bind calcium and fold into the unique the β-roll secondary structure. Several of these domains have been studied in isolation, yielding key insights into their structure/function relationships. These domains are increasingly being used in protein engineering applications, where the calcium-induced control over structure can be exploited to gain new functions. Here we review recent advances in the use of RTX domains in the creation of calcium responsive biomaterials.

Indexed as

beta roll domaincalcium-dependent foldingenvironmentally responsive hydrogelsresponsive biomaterialsRTX domain

Identifiers

PMID30823512
PMCPMC6473919

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.