Evidence map›Paper›PMID 30823457›Full record

ArticleNutrients2019

Comprehensive Preterm Breast Milk Metabotype Associated with Optimal Infant Early Growth Pattern.

Marie-Cécile Alexandre-Gouabau, Thomas Moyon, Agnès David-Sochard, François Fenaille, Sophie Cholet, Anne-Lise Royer, Yann Guitton, Hélène Billard, Dominique Darmaun, Jean-Christophe Rozé and 1 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. The use of choline supplementation in premature newborns: a systematic review.Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo · 2025
    Pooled it
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  10. Metabolism in Retinopathy of Prematurity.Life (Basel, Switzerland) · 2021
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 3 countries.

Marie-Cécile Alexandre-GouabauINRA, UMR1280, Physiopathologie des Adaptations Nutritionnelles, Institut des maladies de l'appareil digestif (IMAD), Centre de Recherche en Nutrition Humaine Ouest (CRNH), Nantes F-44093, France. Marie-Cecile.Alexandre-Gouabau@univ-nantes.fr.ORCID 0000-0002-9966-9593
Thomas MoyonINRA, UMR1280, Physiopathologie des Adaptations Nutritionnelles, Institut des maladies de l'appareil digestif (IMAD), Centre de Recherche en Nutrition Humaine Ouest (CRNH), Nantes F-44093, France. Thomas.Moyon@univ-nantes.fr.
Agnès David-SochardINRA, UMR1280, Physiopathologie des Adaptations Nutritionnelles, Institut des maladies de l'appareil digestif (IMAD), Centre de Recherche en Nutrition Humaine Ouest (CRNH), Nantes F-44093, France. agnes.david@univ-nantes.fr.
François FenailleService de Pharmacologie et d'Immunoanalyse, Laboratoire d'Etude du Métabolisme des Médicaments, CEA, INRA, Université Paris Saclay, MetaboHUB, F-91191 Gif-sur-Yvette, France. francois.fenaille@cea.fr.
Sophie CholetService de Pharmacologie et d'Immunoanalyse, Laboratoire d'Etude du Métabolisme des Médicaments, CEA, INRA, Université Paris Saclay, MetaboHUB, F-91191 Gif-sur-Yvette, France. sophie.cholet@cea.fr.
Anne-Lise RoyerLUNAM Université, ON;IRIS, Laboratoire d'Etude des Résidus et Contaminants dans les Aliments (LABERCA), USC INRA 1329, Nantes F-44307, France. anne-lise.royer@oniris-nantes.fr.
Yann GuittonLUNAM Université, ON;IRIS, Laboratoire d'Etude des Résidus et Contaminants dans les Aliments (LABERCA), USC INRA 1329, Nantes F-44307, France. yann.guitton@oniris-nantes.fr.ORCID 0000-0002-4479-0636
Hélène BillardINRA, UMR1280, Physiopathologie des Adaptations Nutritionnelles, Institut des maladies de l'appareil digestif (IMAD), Centre de Recherche en Nutrition Humaine Ouest (CRNH), Nantes F-44093, France. helene.billard@univ-nantes.fr.
Dominique DarmaunINRA, UMR1280, Physiopathologie des Adaptations Nutritionnelles, Institut des maladies de l'appareil digestif (IMAD), Centre de Recherche en Nutrition Humaine Ouest (CRNH), Nantes F-44093, France. dominique.darmaun@chu-nantes.fr.
Jean-Christophe RozéINRA, UMR1280, Physiopathologie des Adaptations Nutritionnelles, Institut des maladies de l'appareil digestif (IMAD), Centre de Recherche en Nutrition Humaine Ouest (CRNH), Nantes F-44093, France. jeanchristophe.roze@chu-nantes.fr.
Clair-Yves BoquienINRA, UMR1280, Physiopathologie des Adaptations Nutritionnelles, Institut des maladies de l'appareil digestif (IMAD), Centre de Recherche en Nutrition Humaine Ouest (CRNH), Nantes F-44093, France. clair-yves.boquien@univ-nantes.fr.ORCID 0000-0001-6944-5372
PhysioPathologie des Adaptations Nutritionnelles · FRCentre Hospitalier Universitaire de Nantes · FRCommissariat à l'Énergie Atomique et aux Énergies Alternatives · FRUniversité Nantes Angers Le Mans · FRBank of Italy · IT

Funding

Fonds Européen de Développement Economique et Régional 38395, project 6226, 2013-2015
6 · The paper itself

Abstract

Early nutrition impacts preterm infant early growth rate and brain development but can have long lasting effects as well. Although human milk is the gold standard for feeding new born full-term and preterm infants, little is known about the effects of its bioactive compounds on breastfed preterm infants' growth outcomes. This study aims to determine whether breast milk metabolome, glycome, lipidome, and free-amino acids profiles analyzed by liquid chromatography-mass spectrometry had any impact on the early growth pattern of preterm infants. The study population consisted of the top tercile-

Indexed as

Child DevelopmentAdultCarbohydrate MetabolismCohort StudiesFemaleHumansInfantInfant Nutritional Physiological PhenomenaInfant, PrematureLipid MetabolismMetabolomicsMilk, Humanbreast milk metabolomefree amino acidglycomegrowth trajectorylipidomepreterm infant

Identifiers

PMID30823457
PMCPMC6470768
OpenAlexW2916926472

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.