Evidence map›Paper›PMID 30823453›Full record

ArticleMedicines (Basel, Switzerland)2019

The Membrane-Active Phytopeptide Cycloviolacin O2 Simultaneously Targets HIV-1-infected Cells and Infectious Viral Particles to Potentiate the Efficacy of Antiretroviral Drugs.

Samantha L Gerlach, Partha K Chandra, Upal Roy, Sunithi Gunasekera, Ulf Göransson, William C Wimley, Stephen E Braun, Debasis Mondal

Open access · goldAbstract read
In one paragraph

Article in Medicines (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Frontiers in pharmacology · 2022
    Article
  6. Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Samantha L GerlachDepartment of Biology, Division of Science, Technology, Engineering and Mathematics, Dillard University, New Orleans, LA 70122, USA. sgerlach@dillard.edu.
Partha K ChandraDepartment of Pharmacology, Tulane University Medical Center, New Orleans, LA 70112, USA. pchandr1@tulane.edu.
Upal RoyDepartment of Health and Biomedical Sciences, University of Texas Rio Grande Valley, Brownsville, TX 78520, USA. upal.roy@utrgv.edu.ORCID 0000-0002-0325-567X
Sunithi GunasekeraDepartment of Medicinal Chemistry, Uppsala University, 751 23 Uppsala, Sweden. sunithi.gunasekera@fkog.uu.se.ORCID 0000-0002-1089-4015
Ulf GöranssonDepartment of Medicinal Chemistry, Uppsala University, 751 23 Uppsala, Sweden. ulf.goransson@fkog.uu.se.ORCID 0000-0002-5005-9612
William C WimleyDepartment of Biochemistry and Molecular Biology, Tulane University Medical Center, New Orleans, LA 70112, USA. wwimley@tulane.edu.
Stephen E BraunTulane National Primate Research Center, Covington, LA 70112, USA. sbraun@tulane.edu.
Debasis MondalDepartment of Pharmacology, Tulane University Medical Center, New Orleans, LA 70112, USA. dmondal@tulane.edu.
Tulane University · USUppsala University · SEThe University of Texas Rio Grande Valley · US

Funding

Tulane NPRC SPF Sheltered Outdoor Enclosure ExpansionP51OD011104 · OD · TULANE UNIVERSITY OF LOUISIANA · PI L Lee HAMM · 2012 to 2026
$142.4M
Nanodiamond based anti-HIV drug delivery targeted towards the brainR15NS108815 · NINDS · UNIVERSITY OF TEXAS RIO GRANDE VALLEY · PI ROY, UPAL · 2018 to 2018
$433k
NIH HHS P51 OD011104NINDS NIH HHS R15 NS108815
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

antiretroviral drugscyclotidescycloviolacin O2CyO2fusion inhibitorsHIV-1protease inhibitors

Identifiers

PMID30823453
PMCPMC6473583
OpenAlexW2915198841

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.