Evidence map›Paper›PMID 30823422›Full record

ArticleNutrients2019

Dietary Sources of Fructose and Its Association with Fatty Liver in Mexican Young Adults.

Alejandra Cantoral, Alejandra Contreras-Manzano, Lynda Luna-Villa, Carolina Batis, Ernesto A Roldán-Valadez, Adrienne S Ettinger, Adriana Mercado, Karen E Peterson, Martha M Téllez-Rojo, Juan A Rivera

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.

  1. Fatty liver index (FLI): more than a marker of hepatic steatosis.Journal of physiology and biochemistry · 2024
    Pooled it
  2. Pooled it
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  13. Nutritional Approach Targeting Gut Microbiota in NAFLD-To Date.International journal of environmental research and public health · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Alejandra CantoralCONACYT, National Institute of Public Health, Center for Research on Nutrition and Health, Cuernavaca 62100, Mexico. alejandra.cantoral@insp.mx.ORCID 0000-0002-1397-8476
Alejandra Contreras-ManzanoCONACYT, National Institute of Public Health, Center for Research on Nutrition and Health, Cuernavaca 62100, Mexico. alejandra.contreras@insp.mx.
Lynda Luna-VillaCONACYT, National Institute of Public Health, Center for Research on Nutrition and Health, Cuernavaca 62100, Mexico. lyluvi@yahoo.com.mx.
Carolina BatisCONACYT, National Institute of Public Health, Center for Research on Nutrition and Health, Cuernavaca 62100, Mexico. carolina.batis@insp.mx.
Ernesto A Roldán-ValadezHospital General de Mexico "Eduardo Liceaga", Directorate of Research, Mexico City 06720, Mexico. ernest.roldan@usa.net.ORCID 0000-0002-7116-5289
Adrienne S EttingerDepartment of Nutritional Sciences, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA. adrienne.ettinger@gmail.com.
Adriana MercadoCONACYT, National Institute of Public Health, Center for Research on Nutrition and Health, Cuernavaca 62100, Mexico. adrianam@insp.mx.
Karen E PetersonDepartment of Nutritional Sciences, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA. karenep@umich.edu.ORCID 0000-0003-0471-1427
Martha M Téllez-RojoCONACYT, National Institute of Public Health, Center for Research on Nutrition and Health, Cuernavaca 62100, Mexico. mmtellez@insp.mx.
Juan A RiveraCONACYT, National Institute of Public Health, Center for Research on Nutrition and Health, Cuernavaca 62100, Mexico. jrivera@insp.mx.
Instituto Nacional de Salud Pública · MXUniversity of Michigan · USSechenov University · RU

Funding

Regional Pilot And Feasibility Study Grants ProgramP30DK020572 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Mehboob A Hussain · 2013 to 2026
$24.3M
Consejo Nacional de Ciencia y Tecnología 261063NIDDK NIH HHS P30 DK020572
6 · The paper itself

Abstract

Fructose intake has been associated with non-alcoholic fatty liver disease (NAFLD). The objective of this study was to assess the consumption of dietary fructose according to: 1) classification of hepatic steatosis by two indexes and 2) diagnosis of NAFLD by MRI. We conducted a cross-sectional analysis among 100 young adults from Mexico City. The Hepatic Steatosis Index (HSI) and the Fatty Liver Index (FLI) were estimated using Body Mass Index (BMI), waist circumference, and fasting concentrations of glucose, triglycerides, and hepatic enzymes (ALT, AST, GGT). A semi-quantitative food frequency questionnaire was administered to obtain dietary sources of fructose. We estimated the concordance between the hepatic indices and NAFLD and the correlation between the index scores and the percentage of liver fat. Eighteen percent presented NAFLD; 44% and 46% were classified with hepatic steatosis according to HSI and FLI, respectively. We compared dietary intake of fructose by each outcome: HSI, FLI, and NAFLD. Sugar-sweetened beverages (SSB) and juices were consumed significantly more by those with steatosis by FLI and NAFLD suggesting that SSB intake is linked to metabolic alterations that predict the risk of having NAFLD at a young age.

Indexed as

Dietary CarbohydratesFemaleFructoseHumansMaleMexicoNon-alcoholic Fatty Liver DiseaseYoung AdultDietary CarbohydratesFructoseFructosehepatic indexHigh fructose corn syrupNAFLDSugar-sweetened beverages

Identifiers

PMID30823422
PMCPMC6470703
OpenAlexW2916149674

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.