Evidence map›Paper›PMID 30823376›Full record

ArticleNutrients2019

Insulin Controls Triacylglycerol Synthesis through Control of Glycerol Metabolism and Despite Increased Lipogenesis.

Ana Cecilia Ho-Palma, Pau Toro, Floriana Rotondo, María Del Mar Romero, Marià Alemany, Xavier Remesar, José Antonio Fernández-López

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Exploring the effects of excipients on complex coacervation.Journal of colloid and interface science · 2025
    Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Osmolyte-Induced Folding and Stability of Proteins: Concepts and Characterization.Iranian journal of pharmaceutical research : IJPR · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Ana Cecilia Ho-PalmaDepartment of Biochemistry and Molecular Biomedicine, Faculty of Biology, University of Barcelona, 08028 Barcelona, Spain. anace.hop@gmail.com.ORCID 0000-0002-3228-4074
Pau ToroDepartment of Biochemistry and Molecular Biomedicine, Faculty of Biology, University of Barcelona, 08028 Barcelona, Spain. pautoro_20@hotmail.com.
Floriana RotondoDepartment of Biochemistry and Molecular Biomedicine, Faculty of Biology, University of Barcelona, 08028 Barcelona, Spain. floriana.rotondo@gmail.com.ORCID 0000-0002-0688-6856
María Del Mar RomeroDepartment of Biochemistry and Molecular Biomedicine, Faculty of Biology, University of Barcelona, 08028 Barcelona, Spain. marromero@ub.edu.
Marià AlemanyDepartment of Biochemistry and Molecular Biomedicine, Faculty of Biology, University of Barcelona, 08028 Barcelona, Spain. malemany@ub.edu.
Xavier RemesarDepartment of Biochemistry and Molecular Biomedicine, Faculty of Biology, University of Barcelona, 08028 Barcelona, Spain. xremesar@ub.edu.ORCID 0000-0002-9707-7287
José Antonio Fernández-LópezDepartment of Biochemistry and Molecular Biomedicine, Faculty of Biology, University of Barcelona, 08028 Barcelona, Spain. josfernandez@ub.edu.ORCID 0000-0002-2856-7223
Centro de Investigación Biomédica en Red · ESUniversitat de Barcelona · ESUniversidad Nacional del Centro del Perú · PE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Under normoxic conditions, adipocytes in primary culture convert huge amounts of glucose to lactate and glycerol. This "wasting" of glucose may help to diminish hyperglycemia. Given the importance of insulin in the metabolism, we have studied how it affects adipocyte response to varying glucose levels, and whether the high basal conversion of glucose to 3-carbon fragments is affected by insulin. Rat fat cells were incubated for 24 h in the presence or absence of 175 nM insulin and 3.5, 7, or 14 mM glucose; half of the wells contained

Indexed as

AnimalsGlycerolInsulinLipogenesisMaleRatsRats, WistarTriglyceridesGlycerolInsulinTriglyceridesadipocytesglucoseglycerolinsulinlactatelipogenesis

Identifiers

PMID30823376
PMCPMC6470968
OpenAlexW2917035843

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.