Evidence map›Paper›PMID 30823372›Full record

ArticleMicromachines2019

The Effects of Cold Arm Width and Metal Deposition on the Performance of a U-Beam Electrothermal MEMS Microgripper for Biomedical Applications.

Marija Cauchi, Ivan Grech, Bertram Mallia, Pierluigi Mollicone, Nicholas Sammut

Abstract read
In one paragraph

Article in Micromachines, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Marija CauchiDepartment of Mechanical Engineering, Faculty of Engineering, University of Malta, MSD 2080 Msida, Malta. mcauc03@um.edu.mt.ORCID 0000-0002-8974-9194
Ivan GrechDepartment of Microelectronics and Nanoelectronics, Faculty of Information and Communication Technology, University of Malta, MSD 2080 Msida, Malta. ivan.grech@um.edu.mt.
Bertram MalliaDepartment of Metallurgy and Materials Engineering, Faculty of Engineering, University of Malta, MSD 2080 Msida, Malta. bertram.mallia@um.edu.mt.ORCID 0000-0002-4719-0855
Pierluigi MolliconeDepartment of Mechanical Engineering, Faculty of Engineering, University of Malta, MSD 2080 Msida, Malta. pierluigi.mollicone@um.edu.mt.ORCID 0000-0002-4234-0754
Nicholas SammutDepartment of Microelectronics and Nanoelectronics, Faculty of Information and Communication Technology, University of Malta, MSD 2080 Msida, Malta. nicholas.sammut@um.edu.mt.ORCID 0000-0001-7679-604X

Funding

Reach High Scholars Programme - Post-Doctoral Grants, Ministry for Education and Employment, Malta. The grant is part-financed by the European Union, Operational Programme II - Cohesion Policy 2014-2020 - European Social Fund Grant number 254/15/05
6 · The paper itself

Abstract

Microelectromechanical systems (MEMS) have established themselves within various fields dominated by high-precision micromanipulation, with the most distinguished sectors being the microassembly, micromanufacturing and biomedical ones. This paper presents a horizontal electrothermally actuated 'hot and cold arm' microgripper design to be used for the deformability study of human red blood cells (RBCs). In this study, the width and layer composition of the cold arm are varied to investigate the effects of dimensional and material variation of the cold arm on the resulting temperature distribution, and ultimately on the achieved lateral displacement at the microgripper arm tips. The cold arm widths investigated are 14 μ m, 30 μ m, 55 μ m, 70 μ m and 100 μ m. A gold layer with a thin chromium adhesion promoter layer is deposited on the top surface of each of these cold arms to study its effect on the performance of the microgripper. The resultant ten microgripper design variants are fabricated using a commercially available MEMS fabrication technology known as a silicon-on-insulator multi-user MEMS process (SOIMUMPs)™. This process results in an overhanging 25 μ m thick single crystal silicon microgripper structure having a low aspect ratio (width:thickness) value compared to surface micromachined structures where structural thicknesses are of the order of 2 μ m. Finite element analysis was used to numerically model the microgripper structures and coupled electrothermomechanical simulations were implemented in CoventorWare ® . The numerical simulations took into account the temperature dependency of the coefficient of thermal expansion, the thermal conductivity and the electrical conductivity properties in order to achieve more reliable results. The fabricated microgrippers were actuated under atmospheric pressure and the experimental results achieved through optical microscopy studies conformed with those predicted by the numerical models. The gap opening and the temperature rise at the cell gripping zone were also compared for the different microgripper structures in this work, with the aim of identifying an optimal microgripper design for the deformability characterisation of RBCs.

Indexed as

cold arm widthelectrothermal actuationmetal depositionmicroelectromechanical systems (MEMS)microgrippersmicromanipulationred blood cellssingle crystal siliconSOIMUMPs™

Identifiers

PMID30823372
PMCPMC6470733

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.