Evidence map›Paper›PMID 30822381›Full record

ArticleACS nano2019

Water-Dispersible and Biocompatible Iron Carbide Nanoparticles with High Specific Absorption Rate.

Alexis Bordet, Ryan F Landis, YiWei Lee, Gulen Y Tonga, Juan M Asensio, Cheng-Hsuan Li, Pier-Francesco Fazzini, Katerina Soulantica, Vincent M Rotello, Bruno Chaudret

Open access · greenAbstract read
In one paragraph

Article in ACS nano, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 56 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Magnetic Hyperthermia in Glioblastoma Multiforme Treatment.International journal of molecular sciences · 2024
    Review
  6. Article
  7. Review
  8. New Types of Magnetic Nanoparticles for Stimuli-Responsive Theranostic Nanoplatforms.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Review
  9. Review
  10. Commercial CuAngewandte Chemie (International ed. in English) · 2021
    Article
  11. Review
  12. Article
  13. Rapid Millifluidic Synthesis of Stable High Magnetic Moment FeACS applied materials & interfaces · 2020
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Alexis BordetLPCNO, Université de Toulouse, CNRS, INSA, UPS , 135 Avenue de Rangueil , 31077 Toulouse , France.
Ryan F LandisDepartment of Chemistry , University of Massachusetts Amherst , 710 North Pleasant Street , Amherst , Massachusetts 01003 , United States.
YiWei LeeDepartment of Chemistry , University of Massachusetts Amherst , 710 North Pleasant Street , Amherst , Massachusetts 01003 , United States.
Gulen Y TongaDepartment of Chemistry , University of Massachusetts Amherst , 710 North Pleasant Street , Amherst , Massachusetts 01003 , United States.
Juan M AsensioLPCNO, Université de Toulouse, CNRS, INSA, UPS , 135 Avenue de Rangueil , 31077 Toulouse , France.ORCID 0000-0002-9996-6213
Cheng-Hsuan LiDepartment of Chemistry , University of Massachusetts Amherst , 710 North Pleasant Street , Amherst , Massachusetts 01003 , United States.
Pier-Francesco FazziniLPCNO, Université de Toulouse, CNRS, INSA, UPS , 135 Avenue de Rangueil , 31077 Toulouse , France.
Katerina SoulanticaLPCNO, Université de Toulouse, CNRS, INSA, UPS , 135 Avenue de Rangueil , 31077 Toulouse , France.
Vincent M RotelloDepartment of Chemistry , University of Massachusetts Amherst , 710 North Pleasant Street , Amherst , Massachusetts 01003 , United States.ORCID 0000-0002-5184-5439
Bruno ChaudretLPCNO, Université de Toulouse, CNRS, INSA, UPS , 135 Avenue de Rangueil , 31077 Toulouse , France.ORCID 0000-0001-9290-6421
Centre National de la Recherche Scientifique · FRUniversity of Massachusetts Amherst · US

Funding

Targeting of Bio-orthogonal Chemotherapeutic Nanozymes to Tumor-Associated MacrophagesR01EB022641 · NIBIB · UNIVERSITY OF MASSACHUSETTS AMHERST · PI ROTELLO, VINCENT M. · 2017 to 2024
$3.0M
NIBIB NIH HHS R01 EB022641
6 · The paper itself

Abstract

Magnetic nanoparticles are important tools for biomedicine, where they serve as versatile multifunctional instruments for a wide range of applications. Among these applications, magnetic hyperthermia is of special interest for the destruction of tumors and triggering of drug delivery. However, many applications of magnetic nanoparticles require high-quality magnetic nanoparticles displaying high specific absorption rates (SARs), which remains a challenge today. We report here the functionalization and stabilization in aqueous media of highly magnetic 15 nm iron carbide nanoparticles featuring excellent heating power through magnetic induction. The challenge of achieving water solubility and colloidal stability was addressed by designing and using specific dopamine-based ligands. The resulting nanoparticles were completely stable for several months in water, phosphate, phosphate-buffered saline, and serum-containing media. Iron carbide nanoparticles displayed high SARs in water and viscous media (water/glycerol mixtures), even after extended exposition to water and oxygen (SAR up to 1000 W·g

Indexed as

Biocompatible MaterialsCarbon Compounds, InorganicDopamineGlycerolHeLa CellsHumansIron CompoundsLigandsMagnetite NanoparticlesMolecular StructureOxygenWaterBiocompatible MaterialsCarbon Compounds, InorganicDopamineGlyceroliron carbideIron CompoundsLigandsMagnetite NanoparticlesOxygenWaterbiocompatibilityfunctionalizationiron carbidemagnetic hyperthermiananoparticles

Identifiers

PMID30822381
PMCPMC7430224
OpenAlexW2920620497

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.