ArticlePloS one2019
Ten-year analysis of microbiological profile and antibiotic sensitivity for bacterial keratitis in Korea.
Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.
- Corneal collagen cross-linking for bacterial infectious keratitis.The Cochrane database of systematic reviews · 2020Pooled it
- Corynebacterium bovis Keratitis Mimicking Acanthamoeba Infection Following Ocular Trauma.Cureus · 2026Article
- Epidemiology, Microbiology, Antimicrobial Resistance, and Outcomes of Corneal Ulcers: A 10-Year Retrospective Study in Indonesia.Korean journal of ophthalmology : KJO · 2026Article
- Trends of Microorganisms and Antibiotic Resistance Isolated from Patients with Bacterial Keratitis from a Tertiary Hospital in Southeastern Korea: A 26-Year Retrospective Medical Record Review.Antibiotics (Basel, Switzerland) · 2026Article
- Severe Microbial Keratitis in Virgin and Transplanted Cornea-Probability of Visual Acuity Improvement.Journal of clinical medicine · 2024Article
- Increased incidence of methicillin resistantIranian journal of microbiology · 2024Article
- Corticosteroid-Antibiotic Interactions in Bacteria that Cause Corneal Infection.Translational vision science & technology · 2023Article
- Epidemiology and Economic Cost Analysis of Microbial Keratitis from a Tertiary Referral Hospital in Australia.Pathogens (Basel, Switzerland) · 2023Article
- Enhancing Clinical Decision-Making in Complex Corneal Disorders: The Role of In-Vivo Confocal Microscopy.Life (Basel, Switzerland) · 2023Article
- Microbial keratitis in Sao Paulo, Brazil: a 10-year review of laboratory results, epidemiological features, and risk factors.Arquivos brasileiros de oftalmologia · 2023Review
- Deep learning-based classification system of bacterial keratitis and fungal keratitis using anterior segment images.Frontiers in medicine · 2023Article
- The protective effect of URP20 on ocular Staphylococcus aureus and Escherichia coli infection in rats.BMC ophthalmology · 2022Article
- Antibiotic susceptibility pattern of bacterial isolates from microbial keratitis in North and Central India: A multi centric study.Indian journal of ophthalmology · 2022Article
- Infectious Keratitis in Patients with Ocular Sjögren's Syndrome.Korean journal of ophthalmology : KJO · 2022Article
- Spectrum of bacterial keratitis in North India: A retrospective analysis of six years at a tertiary care eye center.Indian journal of ophthalmology · 2022Article
- Pathogens and Antibiotic Susceptibilities of Global Bacterial Keratitis: A Meta-Analysis.Antibiotics (Basel, Switzerland) · 2022Article
- Review
- Medical History, Clinical Features, Treatment Outcome and Its Predictors Among Infectious Keratitis Patients in Jimma University Medical Center, Southwest Ethiopia: Prospective Observational Study.Clinical ophthalmology (Auckland, N.Z.) · 2021Article
- The Incidence and Outcomes of Recurrence of Infection after Therapeutic Penetrating Keratoplasty for Medically-Uncontrolled Infectious Keratitis.Journal of clinical medicine · 2020Article
- The expression of lacrimal androgen-binding proteins in miceInternational journal of ophthalmology · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo investigate the risk factors, microbiological profiles, antibiotic susceptibility patterns, and treatment outcome in patients with bacterial keratitis at a Korean tertiary hospital.
methodsA retrospective chart review was performed of patients who were diagnosed with infectious keratitis and underwent corneal scrapings for cultures at Seoul National University Hospital between 2007 and 2016. Demographics, clinical characteristics, microbiological data, antibiotic resistance and sensitivity, and treatment outcome were collected.
resultsOut of 129 scrapings, bacteria were isolated in 101 samples (78.3%). The most frequent isolates were coagulase-negative Staphylococci (CNS) (15.9%), Staphylococcus aureus (12.1%) and Pseudomonas aeruginosa (10.3%). All gram-positive isolates were sensitive to vancomycin, but methicillin resistance was found in 29.4% of CNS and 15.4% of Staphylococcus aureus. All gram-negative isolates were susceptible to ceftazidime and carbapenem while 11.5%, 3.3% and 2.8% of gram-negative isolates were resistant to gentamicin, tobramycin and amikacin, respectively. Ciprofloxacin resistance was observed in 10.3% of gram-positive isolates and 8.8% of gram-negative isolates. No significant changes were observed in profiles of microbial isolates and antibiotic sensitivity over time. Eight eyes of 101 eyes (7.9%) eventually underwent evisceration for infection control. The use of topical glaucoma medication (p = 0.006) and history of ocular surgery (p = 0.019) were significant risk factors related to evisceration.
conclusionsCNS, Staphylococcus aureus and Pseudomonas aeruginosa were the most common microorganisms responsible for bacterial keratitis. The duo-therapy using vancomycin and ceftazidime should be considered for empirical treatment until the culture and sensitivity results become available.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.