Evidence map›Paper›PMID 30821744›Full record

ArticleOptics letters2019

Local wavefront mapping in tissue using computational adaptive optics OCT.

Fredrick A South, Yuan-Zhi Liu, Pin-Chieh Huang, Tabea Kohlfarber, Stephen A Boppart

Abstract read
In one paragraph

Article in Optics letters, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Fredrick A South
Yuan-Zhi Liu
Pin-Chieh Huang
Tabea Kohlfarber
Stephen A Boppart
University of Illinois Urbana-Champaign · US

Funding

Partnership for Primary Care Imaging of the EarR01EB013723 · NIBIB · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI BOPPART, STEPHEN A · 2011 to 2018
$6.4M
Intraoperative Polarization-Sensitive OCT for Assessing Breast Tumor MarginsR01CA213149 · NCI · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI BOPPART, STEPHEN A · 2017 to 2021
$2.4M
Optical Amplification Microscopy of Weak Back-Scattered LightR01EB023232 · NIBIB · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI BOPPART, STEPHEN A · 2016 to 2019
$1.8M
NCI NIH HHS R01 CA213149NIBIB NIH HHS R01 EB013723NIBIB NIH HHS R01 EB023232
6 · The paper itself

Abstract

The identification and correction of wavefront aberrations is often necessary to achieve high-resolution optical images of biological tissues, as imperfections in the optical system and the tissue itself distort the imaging beam. Measuring the localized wavefront aberration provides information on where the beam is distorted and how severely. We have recently developed a method to estimate the single-pass wavefront aberrations from complex optical coherence tomography (OCT) data. Using this method, localized wavefront measurement and correction using computational OCT was performed in ex vivo tissues. The computationally measured wavefront varied throughout the imaged OCT volumes and, therefore, a local wavefront correction outperformed a global wavefront correction. The local wavefront measurement was also used to generate tissue aberration maps. Such aberration maps could potentially be used as a new form of tissue contrast.

Indexed as

AnimalsBrainChickensImage Processing, Computer-AssistedMammary Glands, AnimalMiceSignal-To-Noise RatioTomography, Optical Coherence

Identifiers

PMID30821744
PMCPMC6827487
OpenAlexW2916558165

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.