ArticleeLife2019
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Open access · goldAbstract read
In one paragraph
Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 43 citations in OpenAlex.
- Uncovering a Sex-Specific cAMP Landscape in Vascular Smooth Muscle.bioRxiv : the preprint server for biology · 2026Article
- CaThe Journal of physiology · 2026Article
- Amyloid β alters vascular CaThe Journal of physiology · 2025Article
- Stimulation of CaScience signaling · 2025Article
- Arterial Myocyte Pannexin 1 Channel Controls Vascular Reactivity in Diabetic Hyperglycemia.Circulation research · 2025Article
- Fluorescent sensors for intracellular signaling in the brain: imaging neurons, glia, and vascular cells.Neurophotonics · 2025Article
- Diabetes Differentially Affects Vascular Reactivity in Isolated Human Arterial and Venous Bypass Grafts.Life (Basel, Switzerland) · 2025Article
- α1Journal of the American Heart Association · 2024Article
- Aberrant splicing of CaCellular and molecular life sciences : CMLS · 2024Article
- Phosphodiesterase in heart and vessels: from physiology to diseases.Physiological reviews · 2024Review
- Adenylyl cyclase isoforms 5 and 6 in the cardiovascular system: complex regulation and divergent roles.Frontiers in pharmacology · 2024Review
- P2YPurinergic signalling · 2023Review
- Diversity of cells and signals in the cardiovascular system.The Journal of physiology · 2023Article
- Oxidative Regulation of Vascular CaAntioxidants (Basel, Switzerland) · 2022Review
- Spatiotemporal Control of Vascular CaCirculation research · 2022Article
- Mechanisms and physiological implications of cooperative gating of clustered ion channels.Physiological reviews · 2022Review
- Adrenergic Regulation of Calcium Channels in the Heart.Annual review of physiology · 2022Review
- Functional tuning of Vascular L-type CaFrontiers in physiology · 2022Review
- Ion channel molecular complexes in vascular smooth muscle.Frontiers in physiology · 2022Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors at 4 institutions in 1 country.
Maria Paz Prada *Department of Pharmacology, University of California, Davis, Davis, United States.
Arsalan U Syed *Department of Pharmacology, University of California, Davis, Davis, United States.
Olivia R Buonarati *Department of Pharmacology, University of California, Davis, Davis, United States.
Gopireddy R ReddyDepartment of Pharmacology, University of California, Davis, Davis, United States.
Matthew A NystoriakDiabetes & Obesity Center, Department of Medicine, University of Louisville, Kentucky, United States.
Debapriya GhoshDepartment of Pharmacology, University of California, Davis, Davis, United States.
Sergi SimóDepartment of Cell Biology & Human Anatomy, University of California, Davis, Davis, United States.
Daisuke SatoDepartment of Pharmacology, University of California, Davis, Davis, United States.
Kent C SasseSasse Surgical Associates, Reno, United States.
Sean M WardDepartment of Physiology & Cell Biology, University of Nevada, Reno, United States.
Luis F SantanaDepartment of Physiology & Membrane Biology, University of California, Davis, Davis, United States.ORCID 0000-0002-4297-8029
Yang K XiangDepartment of Pharmacology, University of California, Davis, Davis, United States.
Johannes W HellDepartment of Pharmacology, University of California, Davis, Davis, United States.
Madeline Nieves-CintrónDepartment of Pharmacology, University of California, Davis, Davis, United States.
Manuel F NavedoDepartment of Pharmacology, University of California, Davis, Davis, United States.ORCID 0000-0001-6864-6594
University of California, Davis · USUniversity of Louisville · USUniversity of Nevada, Reno · USVA Northern California Health Care System · US
Funding
Training Program In Basic & Translational Cardiovascular ScienceT32HL086350 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Martin Cadeiras, David A. Liem · 2008 to 2026
$7.1MMechanisms underlying regional differences in gastric compliance in the stomach.R01DK057236 · NIDDK · UNIVERSITY OF NEVADA RENO · PI KENTON M SANDERS, Sean M Ward · 2000 to 2026
$7.1MCoupling of Vascular Cav1.2 Channels In Health & DiseaseR01HL121059 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI NAVEDO, MANUEL F · 2015 to 2024
$4.5MRole of a-actinin in Cav1.2 FunctionR01AG055357 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI JOHANNES W HELL · 2016 to 2026
$4.0MCalcium Sparklets-Induced Vascular Dysfunction During DiabetesR01HL098200 · NHLBI · UNIVERSITY OF WASHINGTON · PI NAVEDO, MANUEL F · 2010 to 2019
$3.5MInsulin Inhibition of beta-AR Signaling in the MyocardiumR01HL127764 · NHLBI · UNIVERSITY OF IOWA · PI ABEL, E DALE, XIANG, YANG K · 2015 to 2018
$2.4MPredoctoral Training in Pharmacological SciencesT32GM099608 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI HELL, JOHANNES W · 2012 to 2021
$2.2MSignaling by cAMP within postsynaptic nano domains R01NS078792R01NS078792 · NINDS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI HELL, JOHANNES W · 2012 to 2016
$2.0MCardiac Dysfunction in the Met Syndrome: Cross-talk between IR and bAR SignalingR01HL112413 · NHLBI · UNIVERSITY OF IOWA · PI ABEL, E DALE, XIANG, YANG K · 2015 to 2018
$1.6MMRP4 extrudes cAMP for localized regulation of calcium channel activityF31NS086226 · NINDS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI ASFAHA, OLIVIA RUTH · 2013 to 2015
$110kAmerican Heart Association 16SDG27260070American Heart Association 18POST34060234NHLBI NIH HHS R01 HL098200NHLBI NIH HHS R01HL098200NHLBI NIH HHS R01 HL112413NHLBI NIH HHS R01HL112413NHLBI NIH HHS R01 HL121059NHLBI NIH HHS R01HL121059NHLBI NIH HHS R01 HL127764NHLBI NIH HHS R01HL127764NHLBI NIH HHS T32 HL086350NHLBI NIH HHS T32HL086350NIA NIH HHS R01 AG055357NIA NIH HHS R01AG055357NIDDK NIH HHS R01 DK057236NIDDK NIH HHS R01DK57236NIGMS NIH HHS T32 GM099608NIGMS NIH HHS T32GM099608NINDS NIH HHS F31 NS086226NINDS NIH HHS F31NS086226NINDS NIH HHS R01 NS078792NINDS NIH HHS R01NS078792University of California, Davis Academic Federation Innovative Development Award
Abstract
Elevated glucose increases vascular reactivity by promoting L-type Ca
Indexed as
HyperglycemiaMuscle ContractionAnimalsBlood VesselsCalciumCalcium SignalingCyclic AMP-Dependent Protein KinasesMice, Inbred C57BLReceptors, G-Protein-CoupledReceptors, PurinergicCalciumCyclic AMP-Dependent Protein KinasesReceptors, G-Protein-CoupledReceptors, Purinergicarterial tonebiosensorscell biologyextracellular nucleotideshumanion channelsmolecular biophysicsmousestructural biology
Identifiers
What OpenQuestion holds
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LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.