Evidence map›Paper›PMID 30821409›Full record

ArticleAddiction biology2020

High-risk social drinkers and heavy drinkers display similar rates of alcohol consumption.

Matthew E Sloan, Joshua L Gowin, Roshni Janakiraman, Corbin D Ester, Joel Stoddard, Bethany Stangl, Vijay A Ramchandani

Open access · greenAbstract read
In one paragraph

Article in Addiction biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 23 citations in OpenAlex.

  1. Trial
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  4. Does Reflective Thinking Improve the Ability to Plan in Light and Heavy Drinkers? A Clinical-Experimental Model of Metacognition.Medical science monitor : international medical journal of experimental and clinical research · 2026
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  9. High-intensity sweet taste as a predictor of subjective alcohol responses to the ascending limb of an intravenous alcohol prime: an fMRI study.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Matthew E SloanSection on Human Psychopharmacology, National Institute on Alcohol Abuse and Alcoholism, Bethesda, Maryland, USA.ORCID 0000-0003-2172-8802
Joshua L GowinSection on Human Psychopharmacology, National Institute on Alcohol Abuse and Alcoholism, Bethesda, Maryland, USA.
Roshni JanakiramanOffice of the Clinical Director, National Institute on Alcohol Abuse and Alcoholism, Bethesda, Maryland, USA.
Corbin D EsterSection on Human Psychopharmacology, National Institute on Alcohol Abuse and Alcoholism, Bethesda, Maryland, USA.
Joel StoddardDepartment of Psychiatry, School of Medicine, University of Colorado, Denver, Colorado, USA.
Bethany StanglSection on Human Psychopharmacology, National Institute on Alcohol Abuse and Alcoholism, Bethesda, Maryland, USA.
Vijay A RamchandaniSection on Human Psychopharmacology, National Institute on Alcohol Abuse and Alcoholism, Bethesda, Maryland, USA.
National Institute on Alcohol Abuse and Alcoholism · USUniversity of Colorado Denver · US

Funding

Translational Research and Science Education (OUT)P60AA007611 · NIAAA · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI DAVID A. KAREKEN · 2003 to 2026
$45.5M
Alcohol Pharmacokinetics and Pharmacodynamics in HumansZIAAA000466 · NIAAA · NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM · PI RAMCHANDANI, VIJAY ARJUN · 2009 to 2025
$31.2M
Alcohol Pharmacokinetics and Pharmacodynamics in HumansZ01AA000466 · NIAAA · NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM · PI RAMCHANDANI, VIJAY ARJUN · 2006 to 2008
$762k
Neural Correlates of Emotion Regulation in Youth at Risk for AlcoholismR00AA024778 · NIAAA · UNIVERSITY OF COLORADO DENVER · PI GOWIN, JOSHUA LEIGH · 2018 to 2020
$747k
Intramural NIH HHS Z01 AA000466Intramural NIH HHS ZIA AA000466NIAAA NIH HHS P60 AA007611NIAAA NIH HHS R00 AA024778
6 · The paper itself

Abstract

Alcohol consumption is often assessed over weeks to months, but few attempts have been made to characterize alcohol consumption rates at the level of an individual drinking session. Here, we aimed to compare the rate of alcohol consumption in social drinkers at high risk for alcohol use disorder (AUD) and heavy drinkers. One hundred and sixty social drinkers and 48 heavy drinkers participated in an alcohol self-administration study. Social drinkers were classified as low risk or high risk for AUD based on sex, impulsivity, and family history of alcoholism. Participants received a priming dose of intravenous alcohol to assess alcohol-induced craving and completed a 125-minute intravenous alcohol self-administration session to assess rate of achieving a binge-level exposure (blood alcohol concentration greater than or equal to 80 mg%). There were no differences between rates of binging in high-risk and heavy drinkers (hazard ratio = 0.87; 95% CI, 0.48-1.56). Heavy drinkers reported higher levels of craving than high-risk and low-risk drinkers at baseline. However, following a priming dose of alcohol, there were no longer differences in craving between high-risk and heavy drinkers. These results indicate that high-risk social drinkers demonstrate binging behavior that is similar to heavy drinkers, which may be driven by alcohol-induced craving. Prospective studies are needed to elucidate whether these patterns of craving and consumption in high-risk social drinkers are predictive of future AUD.

Indexed as

AdultAlcohol DrinkingAlcoholismBinge DrinkingCravingEthanolFemaleGenetic Predisposition to DiseaseHumansImpulsive BehaviorMaleRiskSelf AdministrationSex FactorsYoung AdultEthanoladdictive behavioralcoholismalcohol self-administrationbinge drinkingcravingrisk factors

Identifiers

PMID30821409
PMCPMC6717699
OpenAlexW2920654367

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.