Evidence map›Paper›PMID 30821230›Full record

ArticleInfection control and hospital epidemiology2019

Antimicrobial therapy for asymptomatic bacteriuria or candiduria in advanced cancer patients transitioning to comfort measures.

Rupak Datta, Tianyun Wang, Mojun Zhu, Louise Marie Dembry, Ling Han, Heather Allore, Vincent Quagliarello, Manisha Juthani-Mehta

Open access · greenAbstract read
In one paragraph

Article in Infection control and hospital epidemiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Management of candiduria in hospitalized patients: a single-center study on the implementation of IDSA guidelines and factors affecting clinical decisions.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Rupak DattaSection of Infectious Diseases,Yale School of Medicine,New Haven, Connecticut.ORCID 0000-0003-2281-7508
Tianyun WangDepartment of Epidemiology of Microbial Diseases,Yale School of Public Health,New Haven, Connecticut.
Mojun ZhuDepartment of Hematology and Oncology,Mayo Clinic,Rochester, Minnesota.
Louise Marie DembrySection of Infectious Diseases,Yale School of Medicine,New Haven, Connecticut.
Ling HanSection of Geriatrics,Yale School of Medicine,New Haven, Connecticut.
Heather AlloreSection of Geriatrics,Yale School of Medicine,New Haven, Connecticut.
Vincent QuagliarelloSection of Infectious Diseases,Yale School of Medicine,New Haven, Connecticut.
Manisha Juthani-MehtaSection of Infectious Diseases,Yale School of Medicine,New Haven, Connecticut.
Yale University · USMayo Clinic · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Yale Study Support Suite (YES3): Dashboard and Web Portal Software Supporting Research Workflow through integrated, customizable REDCap External ModulesP30AG021342 · NIA · YALE UNIVERSITY · PI Denise Esserman · 2002 to 2026
$37.9M
TRAINING IN THE PATHOGENESIS OF INFECTIOUS DISEASEST32AI007517 · NIAID · YALE UNIVERSITY · PI Jaimie Meyer, Albert C Shaw · 1997 to 2026
$6.1M
NCATS NIH HHS UL1 TR001863NIAID NIH HHS T32 AI007517NIA NIH HHS P30 AG021342
6 · The paper itself

Abstract

Among 300 advanced cancer patients with potential urinary tract infection (UTI), 19 had symptomatic UTI. Among remaining patients (n = 281), 21% had asymptomatic bacteriuria or candiduria, and 14% received inappropriate therapy for 279 antimicrobial days. Bacteriuria or candiduria predicted antimicrobial therapy. At 10,000 to <100,000 CFU/mL, the incidence rate ratio [IRR] was 16.9 (95% confidence interval [CI], 6.0-47.2), and at ≥100,000 CFU/mL, the IRR was 27.9 (95% CI, 10.9-71.2).

Indexed as

AgedAged, 80 and overAnti-Bacterial AgentsBacteriuriaCandidiasisCohort StudiesConnecticutFemaleHospitals, UniversityHumansInappropriate PrescribingMaleNeoplasmsTerminal CareUrinary Tract InfectionsAnti-Bacterial Agents

Identifiers

PMID30821230
PMCPMC6482377
OpenAlexW2918855599

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.