ArticleJournal of biological rhythms2019
Effect of White Light Devoid of "Cyan" Spectrum Radiation on Nighttime Melatonin Suppression Over a 1-h Exposure Duration.
Article in Journal of biological rhythms, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 33 citations in OpenAlex.
- Days to re-entrainment following the spring and autumn changes in local clock time: Beyond simple heuristics.Frontiers in photonics · 2024Article
- Long wavelength light reduces the negative consequences of dim light at night.Neurobiology of disease · 2023Article
- EuACS materials Au · 2022Article
- Predicting melatonin suppression by light in humans: Unifying photoreceptor-based equivalent daylight illuminances, spectral composition, timing and duration of light exposure.Journal of pineal research · 2022Article
- Spatial sensitivity of human circadian response: Melatonin suppression from on-axis and off-axis light exposures.Neurobiology of sleep and circadian rhythms · 2021Article
- Comment Concerning the Effects of Light Intensity on Melatonin Suppression in the Review "Light Modulation of Human Clocks, Wake, and Sleep" by A. Prayag et al.Clocks & sleep · 2021Article
- Correlated color temperature and light intensity: Complementary features in non-visual light field.PloS one · 2021Article
- Modeling Circadian Phototransduction: Quantitative Predictions of Psychophysical Data.Frontiers in neuroscience · 2021Article
- Evening types have social jet lag and metabolic alterations in school-age children.Scientific reports · 2020Article
- Article
- Melanopsin contributions to non-visual and visual function.Current opinion in behavioral sciences · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
The intrinsically photosensitive retinal ganglion cells are the main conduit of the light signal emanating from the retina to the biological clock located in the suprachiasmatic nuclei of the hypothalamus. Lighting manufacturers are developing white light sources that are devoid of wavelengths around 480 nm ("cyan gap") to reduce their impact on the circadian system. The present study was designed to investigate whether exposure to a "cyan-gap," 3000 K white light source, spectrally tuned to reduce radiant power between 475 and 495 nm (reducing stimulation of the melanopsin-containing photoreceptor), would suppress melatonin less than a conventional 3000 K light source. The study's 2 phases employed a within-subjects experimental design involving the same 16 adult participants. In Phase 1, participants were exposed for 1 h to 3 experimental conditions over the course of 3 consecutive weeks: 1) dim light control (<5 lux at the eyes); 2) 800 lux at the eyes of a 3000 K light source; and 3) 800 lux at the eyes of a 3000 K, "cyan-gap" modified (3000 K mod) light source. The same protocol was repeated in Phase 2, but light levels were reduced to 400 lux at the eyes. As hypothesized, there were significant main effects of light level ( F
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.