Evidence map›Paper›PMID 30821135›Full record

ArticleJournal of the Turkish German Gynecological Association2019

Polycystic ovarian syndrome: Environmental/occupational, lifestyle factors; an overview

Chaoba Kshetrimayum, Anupama Sharma, Vineet Vashistha Mishra, Sunil Kumar

Open access · diamondAbstract read
In one paragraph

Article in Journal of the Turkish German Gynecological Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
6.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it, 88 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Chaoba KshetrimayumDepartment of Reproductive and Cytotoxicology, ICMR-National Institute of Occupational Health, Ahmedabad, IndiaORCID 0000-0002-4915-5703
Anupama SharmaDepartment of Reproductive and Cytotoxicology, ICMR-National Institute of Occupational Health, Ahmedabad, IndiaORCID 0000-0001-5578-3784
Vineet Vashistha MishraDepartment of Gynecology, Institute of Kidney Diseases, Ahmedabad, India
Sunil KumarFormer, Scientist G & Director-in-Charge NIOH (ICMR), Ahmedabad, IndiaORCID 0000-0001-8624-5727
Gujarat University · INInstitute of Transplantation Sciences · INNational Institute of Occupational Health · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polycystic ovary syndrome (PCOS) is a multifaceted disease of women with infertility that has diverse etiologic factors. Some women may have only a few PCOS-linked symptoms or mild symptoms, whereas others will have severe or all PCOS-linked symptoms. Therefore, PCOS symptoms can differ among women. PCOS is a state of hormonal imbalance, excess terminal hair (hirsutism), hair loss (alopecia), menstruation impairments, metabolic disorders, and cystic appearance on the ovaries. The cysts hamper ovulation, thus reducing the ability of women to become pregnant and result in infertility. The available data suggest that PCOS might originate in utero and the phenotypic appearance of PCOS symptoms may be developed in later life, which could be linked with host factors (endogenous) and exogenous factors like lifestyle, and dietary, environmental or occupational factors. Based upon the available information, it can be postulated that prenatal exposure to excessive androgens might be responsible for androgenization of the fetus, which in turn may alter the program of differentiating target tissues and the phenotypic characteristics of PCOS can be persuaded by exposure of female offspring to various endogenous and exogenous factors at later life. Genetic/host and environmental/lifestyle factors might be related to the pathophysiology of PCOS after prenatal exposure to androgen. Additional studies are necessary to understand the exact mechanism responsible for the manifestation of PCOS because it is a very important issue in female reproduction.

Indexed as

androgenizationanovulationenvironmentalgenetic factorshyperandrogenisminfertilityoccupationalPolycystic ovary syndrome

Identifiers

PMID30821135
PMCPMC6883751
OpenAlexW2918564789

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.