ArticleHistopathology2019
Histological ageing of fractures in infants: a practical algorithm for assessing infants suspected of accidental or non-accidental injury.
Article in Histopathology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Comparing imaging modalities and healing criteria for the estimation of fracture age: a systematic review.International journal of legal medicine · 2026Pooled it
- An unusual blunt force trauma pattern and mechanism to the cranial vault: Investigation of an atypical infant homicide.Journal of forensic sciences · 2023Article
- A method for the development of cranial fracture histology slides.Journal of forensic sciences · 2022Article
- The Repository of Antemortem Injury Response (REPAIR): an online database for skeletal injuries of known ages.International journal of legal medicine · 2022Article
- Utility of micro-CT for dating post-cranial fractures of known post-traumatic ages through 3D measurements of the trabecular inner morphology.Scientific reports · 2022Article
- Estimating the time of skeletal muscle contusion based on the spatial distribution of neutrophils: a practical approach to forensic problems.International journal of legal medicine · 2022Article
- The potential of micro-CT for dating post-cranial bone fractures: a macroscopic, radiographic, and microtomography study of fractures of known post-traumatic ages.International journal of legal medicine · 2021Article
- Histological ageing of fractures in infants: a practical algorithm for assessing infants suspected of accidental or non-accidental injury.Histopathology · 2019Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
aimsThis study is the first to systematically document histological features of fractures of known age in infants (≦12 months). It has been used to develop a tabulated database specifically to guide histopathologists to age fractures in children considered to have suffered accidental or non-accidental injury (NAI). Currently in the United Kingdom there are insufficient pathologists with experience in histological ageing of fractures to meet the medicolegal need for this examination. This study provides a practical tool that will allow those skilled paediatric and forensic pathologists currently involved in assessing infants for evidence of accidental or non-accidental injury a basis for extending their assessment into this area of unmet need. METHODS AND
resultsOne hundred and sixty-nine fractures of known age at death were obtained from 52 anonymised infants over a period of 32 years (1985-2016 inclusive). Sections stained using haematoxylin and eosin (H&E) and Martius scarlet blue (MSB) were used to identify specific histological features and to relate them to fracture age. In 1999 the data were entered into a tabulated database for fractures accumulated between from 1985 to 1998 inclusive. Thereafter cases were added, and at 2-yearly intervals the accumulated data were audited against the previous database and adjustments made.
conclusionsThis paper describes the final data set from the 2017 audit. The study was terminated at the end of 2016, as there had been no material changes in the data set for three consecutive audits.
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