ArticleAIDS and behavior2019
Impaired Neurocognitive Performance and Mortality in HIV: Assessing the Prognostic Value of the HIV-Dementia Scale.
Article in AIDS and behavior, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Living With Chronic HIV Disease in the Antiretroviral Era: The Impact of Neurocognitive Impairment on Everyday Life Functions.Topics in antiviral medicinePooled it
- Cognitive impairment is associated with poorer oral health in people with HIV: evidence from a pilot study.Quintessence international (Berlin, Germany : 1985) · 2026Article
- External Validation of the Charlson Comorbidity Index-based Model for Survival Prediction in Thai Patients Diagnosed with Dementia.BMC geriatrics · 2024Article
- Prediction of incidence of neurological disorders in HIV-infected persons in Taiwan: a nested case-control study.BMC infectious diseases · 2023Article
- Mechanisms underlying HIV-associated cognitive impairment and emerging therapies for its management.Nature reviews. Neurology · 2023Review
- Neuropsychological Test Norms for the Assessment of HIV-Associated Neurocognitive Impairment Among South African Adults.AIDS and behavior · 2023Article
- The Individualized Prediction of Neurocognitive Function in People Living With HIV Based on Clinical and Multimodal Connectome Data.IEEE journal of biomedical and health informatics · 2023Article
- Effects of frailty, geriatric syndromes, and comorbidity on mortality and quality of life in older adults with HIV.BMC geriatrics · 2023Article
- Screening Accuracy of Mini Addenbrooke's Cognitive Examination Test for HIV-Associated Neurocognitive Disorders in People Ageing with HIV.AIDS and behavior · 2022Article
- Neurocognitive status and risk of mortality among people living with human immunodeficiency virus: an 18-year retrospective cohort study.Scientific reports · 2021Article
- Machine learning prediction of neurocognitive impairment among people with HIV using clinical and multimodal magnetic resonance imaging data.Journal of neurovirology · 2021Article
- Increased incidence of glaucoma medication usage in middle-aged Australian males taking antiretroviral medication - a population-based study.Journal of ophthalmic inflammation and infection · 2020Article
Corrections and comments
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Authors and funding
3 authors.
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Abstract
This study examined whether global HIV-associated neurocognitive impairment (NCI), assessed with the HIV-Dementia Scale (HDS), predicted mortality in an ethnically diverse sample of 209 HIV-positive adults. Participants were predominantly in the mid-range of illness at baseline, and followed over 13-years. At baseline, 31 (15%) participants scored in the NCI range (HDS ≤ 10); 58 (28%) died during follow-up. Baseline NCI was significantly associated with earlier mortality (HR = 2.10, 95% CI [1.10-4.00]) independent of sociodemographic and HIV disease-related covariates. Less errors on the antisaccade task, an index of executive/attention control, was the only HDS subtest predicting earlier mortality (HR = 0.72, 95% CI [0.58-0.90]). In the absence of an AIDS-defining condition, NCI, particularly in the executive/attention domain, is an independent prognostic marker of mortality in a diverse HIV-positive cohort. These findings highlight the clinical utility of brief cognitive screening measures in this population.
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