Evidence map›Paper›PMID 30820829›Full record

ArticleNeuroscience bulletin2019

Up-regulation of P2X7 Receptors Contributes to Spinal Microglial Activation and the Development of Pain Induced by BmK-I.

Jingjing Zhou, Xiaoxue Zhang, You Zhou, Bin Wu, Zhi-Yong Tan

Open access · greenAbstract read
In one paragraph

Article in Neuroscience bulletin, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
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  8. Article
  9. The effect and mechanism of exercise for post-stroke pain.Frontiers in molecular neuroscience · 2022
    Review
  10. Article
  11. Oxaliplatin Depolarizes the IB4Frontiers in molecular neuroscience · 2021
    Article
  12. Review
  13. Pain-related toxins in scorpion and spider venoms: a face to face with ion channels.The journal of venomous animals and toxins including tropical diseases · 2021
    Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Jingjing ZhouLaboratory of Neuropharmacology and Neurotoxicology, Shanghai University, Shanghai, 200444, China.
Xiaoxue ZhangLaboratory of Neuropharmacology and Neurotoxicology, Shanghai University, Shanghai, 200444, China.
You ZhouLaboratory of Neuropharmacology and Neurotoxicology, Shanghai University, Shanghai, 200444, China.
Bin WuLaboratory of Neuropharmacology and Neurotoxicology, Shanghai University, Shanghai, 200444, China.
Zhi-Yong TanDepartment of Pharmacology and Toxicology and Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN, 46202, USA. zt2@iupui.edu.ORCID http://orcid.org/0000-0001-7696-113X
Shanghai University · CNIndiana University School of Medicine

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous work has demonstrated that the sensitization of spinal neurons and microglia is important in the development of pain behaviors induced by BmK I, a Na

Indexed as

AnimalsAstrocytesInterleukin-1betaMaleMicrogliaPainPurinergic P2X Receptor AntagonistsRatsRats, Sprague-DawleyReceptors, Purinergic P2X7Scorpion VenomsSpinal Cord Dorsal HornIL1B protein, ratInterleukin-1betamakatoxin IPurinergic P2X Receptor AntagonistsReceptors, Purinergic P2X7Scorpion VenomsBmK IBrilliant Blue GInterleukin 1βMicrogliaP2X7 receptorSpinal dorsal horn

Identifiers

PMID30820829
PMCPMC6616629
OpenAlexW2919159776

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.