Evidence map›Paper›PMID 30820720›Full record

ArticleInflammopharmacology2019

The kinin B

Nara L M Quintão, Lilian W Rocha, Gislaine F da Silva, Ana F Paszcuk, Marianne N Manjavachi, Allisson F Bento, Kathryn Ana B S da Silva, Maria M Campos, João B Calixto

Erratum issuedOpen access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Inflammopharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Kinin BPharmaceutics · 2023
    Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Nara L M QuintãoPrograma de Pós-graduação em Ciências Farmacêuticas, Centro de Ciências da Saúde, Universidade do Vale do Itajaí, Rua Uruguai, No. 458, Bloco F6, CCS, sala 301, Itajaí, SC, CEP 88302-202, Brazil. nara.quintao@univali.br.ORCID http://orcid.org/0000-0001-8305-9339
Lilian W RochaPrograma de Pós-graduação em Ciências Farmacêuticas, Centro de Ciências da Saúde, Universidade do Vale do Itajaí, Rua Uruguai, No. 458, Bloco F6, CCS, sala 301, Itajaí, SC, CEP 88302-202, Brazil.
Gislaine F da SilvaPrograma de Pós-graduação em Ciências Farmacêuticas, Centro de Ciências da Saúde, Universidade do Vale do Itajaí, Rua Uruguai, No. 458, Bloco F6, CCS, sala 301, Itajaí, SC, CEP 88302-202, Brazil.
Ana F PaszcukDepartamento de Farmacologia, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Florianópolis, SC, Brazil.
Marianne N ManjavachiDepartamento de Farmacologia, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Florianópolis, SC, Brazil.
Allisson F BentoDepartamento de Farmacologia, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Florianópolis, SC, Brazil.
Kathryn Ana B S da SilvaPrograma de Pós-graduação em Ciências Farmacêuticas, Centro de Ciências da Saúde, Universidade do Vale do Itajaí, Rua Uruguai, No. 458, Bloco F6, CCS, sala 301, Itajaí, SC, CEP 88302-202, Brazil.
Maria M CamposCentro de Pesquisa em Toxicologia e Farmacologia, Escola de Ciências da Saúde, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre, RS, 90619-900, Brazil.
João B CalixtoDepartamento de Farmacologia, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Florianópolis, SC, Brazil.
Universidade do Vale do Itajaí · BRUniversidade Federal de Santa Catarina · BRPontifícia Universidade Católica do Rio Grande do Sul · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tumour necrosis factor (TNF) and kinins have been associated with neuropathic pain-like behaviour in numerous animal models. However, the way that they interact to cause neuron sensitisation remains unclear. This study assessed the interaction of kinin receptors and TNF receptor TNFR1/p55 in mechanical hypersensitivity induced by an intraneural (i.n.) injection of rm-TNF into the lower trunk of brachial plexus in mice. The i.n. injection of rm-TNF reduced the mechanical withdrawal threshold of the right forepaw from the 3rd to the 10th day after the injection, indicating that TNF1/p55 displays a critical role in the onset of TNF-elicited neuropathic pain. The connection between TNF1/p55 and kinin B

Indexed as

AnimalsBrachial PlexusBradykinin B1 Receptor AntagonistsBradykinin B2 Receptor AntagonistsDisease Models, AnimalFemaleMiceMice, Inbred C57BLMice, KnockoutNeuralgiaReceptor, Bradykinin B1Receptor, Bradykinin B2Receptors, Tumor Necrosis Factor, Type ITumor Necrosis Factor-alphaBradykinin B1 Receptor AntagonistsBradykinin B2 Receptor AntagonistsReceptor, Bradykinin B1Receptor, Bradykinin B2Receptors, Tumor Necrosis Factor, Type ITnfrsf1a protein, mouseTumor Necrosis Factor-alphaBrachial plexusCarboxypeptidaseCytokineKinin receptorsNeuropathic painTNF

Identifiers

PMID30820720
OpenAlexW2920328544

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.