ReviewDigestive diseases and sciences2019
Diagnosis and Treatment Patterns in Celiac Disease.
Review in Digestive diseases and sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 1 synthesis or guideline pooled it, 63 citations in OpenAlex.
- Body mass index in children with newly diagnosed celiac disease: A systematic review and meta-analysis.European journal of pediatrics · 2025Pooled it
- Review
- Celiac disease in children with focus on symptoms and quality of life.Scientific reports · 2025Article
- Recent advances in the diagnosis of celiac disease.World journal of gastroenterology · 2025Article
- Delay in Celiac Disease Diagnosis Among Patients with High-Risk Screening Conditions: Results from a United States Claims Database.Journal of clinical medicine · 2025Article
- Hypoalbuminemia as an Unusual Presentation of Undiagnosed Atypical Celiac Disease in an 84-Year-Old Woman.Annals of geriatric medicine and research · 2025Article
- Toward Precision Medicine in Celiac Disease: Emerging Roles of Multiomics and Artificial Intelligence.Analytical cellular pathology (Amsterdam) · 2025Review
- Advances in understanding and managing celiac disease: Pathophysiology and treatment strategies.World journal of gastroenterology · 2024Article
- Importance of an Ongoing Nutritional Counselling Intervention on Eating Habits of Newly Diagnosed Children with Celiac Disease.Nutrients · 2024Article
- Prevalence of eating disorders in patients with celiac disease: a comparative study with healthy individuals.Revista da Associacao Medica Brasileira (1992) · 2024Article
- Celiac Disease: A Review from Genetic to Treatment.Iranian biomedical journal · 2024Review
- Review
- Celiac Disease in Moroccan Children: Diagnostic Characteristics and Determinants of Diagnosis Delay.Cureus · 2023Article
- Rapid Anti-tTG-IgA Screening Test for Early Diagnosis of Celiac Disease in Pediatric Populations.Nutrients · 2023Article
- Article
- Mode of presentation and performance of serology assays for diagnosing celiac disease: A single-center study in the United Arab Emirates.Frontiers in nutrition · 2023Article
- Article
- The Impact of Zinc and Zinc Homeostasis on the Intestinal Mucosal Barrier and Intestinal Diseases.Biomolecules · 2022Review
- Biochemical abnormalities among patients referred for celiac disease antibody blood testing in a primary health care setting.Scientific reports · 2022Observational
- Automated detection of celiac disease using Machine Learning Algorithms.Scientific reports · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Celiac disease (CD) is an immune-mediated gastrointestinal (GI) disorder driven by innate and adaptive immune responses to gluten. Presentation of CD has changed over time, with non-GI symptoms, such as anemia and osteoporosis, presenting more commonly. With improved screening and diagnostic methods, the reported prevalence of CD has increased globally, and there is considerable global variation in diagnostic and treatment practices. The objective of this study was to describe the current state of CD diagnosis and treatment patterns. A targeted review of literature from MEDLINE, Embase, the Cochrane Library, and screening of relevant conference abstracts was performed. The generally recommended diagnostic approach is GI endoscopy with small bowel biopsy; however, in selected patients, biopsy may be avoided and diagnosis based on positive serology and clinical symptoms. Diagnosis often is delayed; the average diagnostic delay after symptom onset is highly variable and can last up to 12 years. Barriers to accurate and timely diagnosis include atypical presentation, lack of physician awareness about current diagnostic criteria, misdiagnosis, and limited access to specialists. Currently, strict adherence to a gluten-free diet (GFD) is the only recommended treatment, which is not successful in all patients. Only one-third of patients are monitored regularly following diagnosis. Unmet needs for CD include improvements in the accuracy and timeliness of diagnosis, and the development of treatments for both refractory CD and GFD nonresponsive CD. Further research should investigate the impact of education about gluten-free eating and the availability of gluten-free foods support adherence and improve outcomes in patients with CD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.