ArticleHeart and vessels2019
Real-world survival data of device-related thrombus following left atrial appendage closure: 4-year experience from a single center.
Article in Heart and vessels, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.
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Who cites it
16 citing papers in PubMed, 3 syntheses or guidelines pooled it, 23 citations in OpenAlex.
- An updated meta-analysis of device related thrombus following left atrial appendage closure in patients with atrial fibrillation.Frontiers in cardiovascular medicine · 2022Pooled it
- Systematic review on left atrial appendage closure with the LAmbre device in patients with non-valvular atrial fibrillation.BMC cardiovascular disorders · 2020Pooled it
- Residual flow may increase the risk of adverse events in patients received combined catheter ablation and transcatheter left atrial appendage closure for nonvalvular atrial fibrillation: a meta-analysis.BMC cardiovascular disorders · 2019Pooled it
- 3-Year outcomes after left atrial appendage closure in patients with nonvalvular atrial fibrillation: cardiomyopathy related with increased death and stroke rate.BMC cardiovascular disorders · 2023Trial
- Steerable Delivery Sheath for Optimized LAA Closure: First Experience and Procedural Outcomes.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2025Article
- Does Spontaneous Echo Contrast in the Left Atrial Appendage Increase Thromboembolism Risk After Left Atrial Appendage Closure? A Retrospective Study on Its Impact on Device-Related Thrombosis and Arterial Thromboembolic Events.Cardiovascular therapeutics · 2025Article
- Comparison of prognosis and analysis of related risk factors among three different left atrial appendage occlusion procedures in patients with atrial fibrillation.Frontiers in cardiovascular medicine · 2025Article
- Article
- Management of complications associated with percutaneous left atrial appendage closure with or without ablation: experience from 512 cases over a 4-year period.Frontiers in cardiovascular medicine · 2024Article
- Comparison of different quantitative evaluation protocols for peri-device leak detection using cardiac computed tomography angiography after left atrial appendage closure.The international journal of cardiovascular imaging · 2023Article
- Diagnostic value of real-time four-dimensional transesophageal echocardiography on the implant-related thrombus.Frontiers in cardiovascular medicine · 2023Article
- Device-Related Thrombus After Left Atrial Appendage Occlusion: The Villain of the Piece.JACC. Clinical electrophysiology · 2023Article
- Comparison of intracardiac vs. transesophageal echocardiography for "one-stop" procedures of combined radiofrequency catheter ablation and left atrial appendage closure with the Watchman device in the treatment of atrial fibrillation.Frontiers in cardiovascular medicine · 2023Article
- 2019 Chinese expert consensus statement on left atrial appendage closure in patients with atrial fibrillation.Pacing and clinical electrophysiology : PACE · 2022Review
- Design and Rationale of the Swiss-Apero Randomized Clinical Trial: Comparison of Amplatzer Amulet vs Watchman Device in Patients Undergoing Left Atrial Appendage Closure.Journal of cardiovascular translational research · 2021Article
- Device related thrombosis after left atrial appendage occlusion: does thrombus location always predicts its origin?Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2021Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study aimed to estimate the incidence and risk factors of device-related thrombus (DRT) following percutaneous left atrial appendage closure (LAAC) in real-world practices. Between February 2012 and December 2016, 319 consecutive patients with atrial fibrillation underwent percutaneous LAAC using WATCHMAN, WATCHMAN Flx, Amplatzer cardiac plug, and Amulet devices. All patients underwent transesophageal echocardiography (TEE) at a minimum of three time points; periprocedurally, at 45 days, and at 6 months. Other clinical parameters were also evaluated, and a comparison between patients with DRT and those not suffering from DRT was done. The percutaneous LAAC was successfully performed in 97.8% of the patients. DRT was detected in 14 (4.49%) patients; of the 14 patients, DRT was detected in 3 patients at acute phase, 8 patients at subacute phase, 2 patients at late phase and 1 patient at very late phase. Most of the DRT originated from the central screw of device. In 6 out of 14 patients, DRT was successfully resolved by oral anticoagulation. Higher HAS-BLED score (4.1 ± 1.2 vs. 3.5 ± 1.1, p = 0.042) was more frequent in patients with DRT. Multivariable analysis showed that residual peri-device leak may result in a predisposition to DRT (p = 0.023). The incidence of DRT after percutaneous LAAC was acceptable, as a part of the DRT was resolved with oral anticoagulation. Residual peri-device leak was associated with DRT. Optimal implantation without peri-device gap, individual antithrombotic regimens, and careful monitoring with TEE follow-up could be conducive to the prevention of DRT.
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