Evidence map›Paper›PMID 30820584›Full record

ReviewIntensive care medicine2019

Management of donation after brain death (DBD) in the ICU: the potential donor is identified, what's next?

Ignacio Martin-Loeches, Alberto Sandiumenge, Julien Charpentier, John A Kellum, Alan M Gaffney, Francesco Procaccio, Glauco A Westphal

Abstract readReview
PubMed Publisher
In one paragraph

Review in Intensive care medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Management of Potential Organ Donor: Indian Society of Critical Care Medicine-Position Statement.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2024
    Article
  6. Characterizing proximity and transfers of deceased organ donors to donor care units in the United States.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2024
    Article
  7. Assessing Outcomes of Patients Subject to Intensive Care to Facilitate Organ Donation: A Spanish Multicenter Prospective Study.Transplant international : official journal of the European Society for Organ Transplantation · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Recommendations for Evaluation and Selection of Deceased Organ Donor: Position Statement of ISCCM.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2022
    Article
  12. Hemodynamic management in brain dead donors.World journal of transplantation · 2021
    Review
  13. Article
  14. Article
  15. Increase in Cadaver Organ Donation Rate at a Tertiary Care Hospital: 23 Years of Experience.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2020
    Article
  16. Variability in deceased donor care in Canada: a report of the Canada-DONATE cohort study.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2020
    Article
  17. Brain Death and Management of Potential Organ Donor: An Indian Perspective.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2019
    Review
  18. Article
  19. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ignacio Martin-LoechesDonor Coordination Unit, Department of Intensive Care Medicine, Multidisciplinary Intensive Care Research Organization (MICRO), St James's Hospital, James's St N, Ushers, Dublin, D03 VX82, Ireland. drmartinloeches@gmail.com.ORCID http://orcid.org/0000-0002-5834-4063
Alberto SandiumengeDonor Coordination Unit, Vall D'Hebron University Hospital, Barcelona, Spain.
Julien CharpentierMedical Intensive Care Unit, Cochin Hospital, Paris, France.
John A KellumUniversity of Pittsburgh, Pittsburgh, PA, USA.
Alan M GaffneyDepartment of Anaesthesia and Critical Care, Beaumont Hospital, Dublin, Ireland.
Francesco ProcaccioNational Technical Transplant Council, Italian Health Institute, Rome, Italy.
Glauco A WestphalBrazilian Research in Intensive Care Network, BRICNet, São Paulo, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The success of any donation process requires that potential brain-dead donors (PBDD) are detected and referred early to professionals responsible for their evaluation and conversion to actual donors. The intensivist plays a crucial role in organ donation. However, identification and referral of PBDDs may be suboptimal in the critical care environment. Factors influencing lower rates of detection and referral include the lack of specific training and the need to provide concomitant urgent care to other critically ill patients. Excellent communication between the ICU staff and the procurement organization is necessary to ensure the optimization of both the number and quality of organs transplanted. The organ donation process has been improved over the last two decades with the involvement and commitment of many healthcare professionals. Clinical protocols have been developed and implemented to better organize the multidisciplinary approach to organ donation. In this manuscript, we aim to highlight the main steps of organ donation, taking into account the following: early identification and evaluation of the PBDD with the use of checklists; donor management, including clinical maintenance of the PBDD with high-quality intensive care to prevent graft failure in recipients and strategies for optimizing donated organs by simplified care standards, clinical guidelines and alert tools; the key role of the intensivist in the donation process with the interaction between ICU professionals and transplant coordinators, nurse protocol managers, and communication skills training; and a final remark on the importance of the development of research with further insight into brain death pathophysiology and reversible organ damage.

Indexed as

Brain DeathDonor SelectionHumansIntensive Care UnitsReferral and ConsultationBrain deathCritical careEarly goalIcuOrgan donationTransplantation

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.