Evidence map›Paper›PMID 30820446›Full record

ArticleeNeuro

The Role of the Voltage-Gated Potassium Channel Proteins Kv8.2 and Kv2.1 in Vision and Retinal Disease: Insights from the Study of Mouse Gene Knock-Out Mutations.

Nathan S Hart, Jessica K Mountford, Valentina Voigt, Paula Fuller-Carter, Melanie Barth, Jeanne M Nerbonne, David M Hunt, Livia S Carvalho

Open access · goldAbstract read
In one paragraph

Article in eNeuro. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 42 citations in OpenAlex.

  1. Kv2.1/Kv8.2 Channels Regulate Fluid Homeostasis in the Outer Retina.bioRxiv : the preprint server for biology · 2026
    Article
  2. Article
  3. International journal of molecular sciences · 2025
    Article
  4. Cells · 2025
    Article
  5. Article
  6. The Electrically Silent Kv5.1 Subunit Forms Heteromeric Kv2 Channels in Cortical Neurons and Confers Distinct Functional Properties.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  7. KCNG4 Genetic Variant Linked to Migraine Prevents Expression of KCNB1.International journal of molecular sciences · 2024
    Article
  8. A versatile functional interaction between electrically silent KCellular and molecular life sciences : CMLS · 2024
    Article
  9. The origins of the full-field flash electroretinogram b-wave.Frontiers in molecular neuroscience · 2023
    Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Sensing through Non-Sensing Ocular Ion Channels.International journal of molecular sciences · 2020
    Review
  16. Article
  17. Ophthalmic genetics · 2020
    Review
  18. Review
  19. Two-color pupillometry in KCNV2 retinopathy.Documenta ophthalmologica. Advances in ophthalmology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Nathan S HartSchool of Biological Sciences, The University of Western Australia, Perth, Western Australia 6009, Australia.ORCID 0000-0002-7289-9399
Jessica K MountfordSchool of Biological Sciences, The University of Western Australia, Perth, Western Australia 6009, Australia.ORCID 0000-0002-3293-6327
Valentina VoigtCentre for Ophthalmology and Vision Science, Lions Eye Institute, The University of Western Australia, Perth, Western Australia 6009, Australia.
Paula Fuller-CarterCentre for Ophthalmology and Vision Science, Lions Eye Institute, The University of Western Australia, Perth, Western Australia 6009, Australia.
Melanie BarthCentre for Ophthalmology and Vision Science, Lions Eye Institute, The University of Western Australia, Perth, Western Australia 6009, Australia.
Jeanne M NerbonneDepartment of Developmental Biology, Washington University School of Medicine, St. Louis, MO 63110.ORCID 0000-0001-8334-8499
David M HuntSchool of Biological Sciences, The University of Western Australia, Perth, Western Australia 6009, Australia.
Livia S CarvalhoCentre for Ophthalmology and Vision Science, Lions Eye Institute, The University of Western Australia, Perth, Western Australia 6009, Australia.ORCID 0000-0002-3909-5778
Lions Eye Institute · AUThe University of Western Australia · AUWashington University in St. Louis · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mutations in the

Indexed as

AnimalsCone DystrophyFemaleGene Knockout TechniquesMice, Inbred C57BLMice, KnockoutMutationPotassium Channels, Voltage-GatedRetinaShab Potassium ChannelsSynaptic TransmissionVision, OcularKcnb1 protein, mouseKcnv2 protein, mousePotassium Channels, Voltage-GatedShab Potassium Channelscone dystrophyelectroretinogramphotoreceptorspotassium channelsretinaretinal degeneration

Identifiers

PMID30820446
PMCPMC6393689
OpenAlexW2914850706

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.