Evidence map›Paper›PMID 30820281›Full record

ArticleJournal of ophthalmic & vision research

Comparative Assessment of Tear Function Tests, Tear Osmolarity, and Conjunctival Impression Cytology between Patients with Pterygium and Healthy Eyes.

Masoud Safarzadeh, Sahel Heidari, Parvin Azizzadeh, Kourosh Sheibani, Nader Nassiri, Laleh Heidari, Sattar Aghataheri

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Article in Journal of ophthalmic & vision research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

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4citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Masoud SafarzadehDepartment of Optometry, Faculty of Rehabilitation Sciences, Iran University of Medical Sciences, Tehran, Iran.ORCID 0000-0003-1728-6773
Sahel HeidariDepartment of Immunology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.ORCID 0000-0002-4573-4900
Parvin AzizzadehBahman Ophthalmology Research Center, Bahman Hospital, Tehran, Iran.ORCID 0000-0003-0182-4223
Kourosh SheibaniBasir Eye Safety Research Center, Basir Eye Clinic, Tehran, Iran.
Nader NassiriOphthalmic Research Center, Department of Ophthalmology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Laleh HeidariDepartment of Medical Genetics, Shahid Beheshti University of Medical Sciences, Tehran, Iran.ORCID 0000-0002-0002-9052
Sattar AghataheriDepartment of Optometry, Faculty of Rehabilitation Sciences, Iran University of Medical Sciences, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo compare histologic abnormalities of tear film and tear osmolarity between normal eyes and eyes with pterygium.

methodsThis was a prospective, hospital-based, case-control study involving 95 patients (65 men, 30 women) with unilateral pterygium. The tear meniscus height (TMH), Schirmer's test-1 (SCH-1) score, Rose Bengal staining (RBS) score, tear film breakup time (TBUT), tear osmolarity (TO), and conjunctival impression cytology (CIC) were assessed in both eyes. The Chi-square and Student's

resultsThe mean patient age was 50.9 years, with the largest age group being the 45-55 year-old bracket across both genders. Most patients (82.1%) had nasal pterygium, and 80% were involved in outside activities. The mean assessment values in the case and control groups were as follows: TMH, 0.21 vs. 0.24 mm; SCH-1, 13.2 vs. 17.8 mm; RBS, 4.38 vs. 2.51 points; TBUT, 8.7 vs. 13.2 seconds; TO, 306 vs. 299 mOsm/L (

conclusionThis study showed that the quantity and quality of tear film, as well as the number of goblet cells, decreased, but the tear osmolarity increased in eyes with pterygium. Furthermore, the TMH, RBS results, TBUT, and CIC have more precise state of the patient's tear condition with the disease of the pterygium.

Indexed as

Conjunctival Impression CytologyPterygiumRose Bengal StainingSchirmer's TestTear Breakup TimeTear Meniscus HeightTear Osmolarity

Identifiers

PMID30820281
PMCPMC6388519

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.