ReviewWorld journal of cardiology2019
Heart valve disease in elderly.
Review in World journal of cardiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 1 synthesis or guideline pooled it, 87 citations in OpenAlex.
- Effect of direct oral anticoagulants in patients with atrial fibrillation with mitral or aortic stenosis: A review.Frontiers in cardiovascular medicine · 2022Pooled it
- Innovation and Challenges in Materials for Transcatheter Aortic Valves.Journal of cardiovascular translational research · 2026Review
- Predictors of echocardiographic abnormalities in asymptomatic individuals with increased cardiothoracic ratio detected on chest radiography.American heart journal plus : cardiology research and practice · 2026Article
- Lymphatic dysfunction and ZFP36 deficiency contribute to myxomatous valve degeneration in Marfan syndrome mice.The Journal of clinical investigation · 2026Article
- Interconnected Pathways and Therapeutic Implications for Cardiovascular Aging and Diseases.JACC. Asia · 2026Review
- Hemodynamic and microcirculatory early adaptations following transcatheter aortic valve implantation (TAVI): A physiological pilot study.European journal of clinical investigation · 2026Article
- The global, regional, and national burden of non-rheumatic degenerative mitral valve disease from 1990 to 2021 and forecast for 2050.Frontiers in cardiovascular medicine · 2026Article
- Contemporary Review of Outcomes in Patients Undergoing Transcatheter Aortic Valve Replacement with Concomitant Mitral Stenosis.Current cardiology reviews · 2026Review
- Gender Matters: A State-of-the-Art Review of Transcatheter Structural Interventions in Older Women Vs Men.JACC. Advances · 2025Article
- Artificial intelligence prediction of age from echocardiography as a marker for cardiovascular disease.NPJ digital medicine · 2025Article
- Long-term effect of transcatheter mitral valve edge-to-edge repair on left ventricular function and mitral regurgitation severity: a single-center experience.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2025Article
- TAVR in older adults with cardiogenic shock: current practice and future direction.Journal of geriatric cardiology : JGC · 2025Article
- Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues.ESC heart failure · 2025Review
- Stuck Prosthetic Valves: Clinical Implications of Pannus Formation and Gradient Measurement in Surgical Outcomes.Journal of clinical medicine · 2025Article
- Optimizing Anticoagulation in Valvular Heart Disease: Navigating NOACs and VKAs.Journal of personalized medicine · 2024Review
- Age-Related Outcomes in Heart Failure with Mildly Reduced Ejection Fraction.Journal of clinical medicine · 2024Article
- Wnt Signaling Inhibition Prevents Postnatal Inflammation and Disease Progression in Mouse Congenital Myxomatous Valve Disease.Arteriosclerosis, thrombosis, and vascular biology · 2024Article
- Article
- The impact of transcatheter aortic valve implantation (TAVI) on mitral regurgitation - a single center study.Cardiology journal · 2024Article
- Strengthened Decellularized Porcine Valves via Polyvinyl Alcohol as a Template Improving Processability.Polymers · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The incidence of heart valve disease increases significantly with age. Degenerative abnormalities associated with severe aortic stenosis and mitral and tricuspid regurgitation are found in not less than 10% of the population aged ≥ 75 years. Surgical treatment has been considered for years to be the treatment of choice. However, it was not uncommonly associated with high perioperative morbidity and mortality due to frequent comorbidities and overall frailty conditions of these patients. Conventional risk scores such as Society of Thoracic Surgeons and European System for Cardiac Operative Risk Evaluation may underestimate the risk of surgery in elderly patients, leading to inappropriate surgical indication. On the other hand, at least 30% of patients with severe conditions are left untreated due to prohibitive surgical risk. Interventional procedures, which are in continuous development, may be actually considered for high risk patients and, as recent results suggest, also for intermediate risk patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.