Evidence map›Paper›PMID 30819934›Full record

Observational studyScience (New York, N.Y.)2019

Binodal, wireless epidermal electronic systems with in-sensor analytics for neonatal intensive care.

Ha Uk Chung, Bong Hoon Kim, Jong Yoon Lee, Jungyup Lee, Zhaoqian Xie, Erin M Ibler, KunHyuck Lee, Anthony Banks, Ji Yoon Jeong, Jongwon Kim and 35 more

2 registry-linked trialsAbstract readObservational Study
In one paragraph

Observational study in Science (New York, N.Y.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 204 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
204citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04723654 recruitingnot on this map

Evaluating Wearable Smart Sensors for Continuous Measurement of Vital Signs in ICU

TypeobservationalSponsorAnn & Robert H Lurie Children's Hospital of ChicagoRan2018 to 2028Enrolled500ConditionsPrematurityArmsWireless Wearable Vital Sign Monitor
NCT06423118 recruitingnot on this mapstarted 2024, after this paper: background citation

Cross-sectional Investigation of Sleep Apnea and Cognition in Older Adults Using the ANNE Vital Sign System

TypeobservationalSponsorSunnybrook Health Sciences CentreRan2024 to 2034Enrolled300ConditionsSleep, Cognition, AgingArmsANNE Vital Sign System
3 · Its place in the literature

Who cites it

204 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Thickness-Gradient Liquid Metal Connectors for Seamless Electrophysiological Sensors.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
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  18. Intrinsic PPG-ECG Coupling for Accurate and Low-Power Blood Pressure Monitoring.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  19. Article
  20. Soft, Flexible, and Stretchable Platforms for Tissue-Interfaced Bioelectronics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review

144 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

45 authors.

Ha Uk ChungSimpson Querrey Institute, Northwestern University, Chicago, IL 60611, USA.ORCID http://orcid.org/0000-0003-3592-8944
Bong Hoon KimSimpson Querrey Institute, Northwestern University, Chicago, IL 60611, USA.ORCID http://orcid.org/0000-0002-4610-0176
Jong Yoon LeeFrederick Seitz Materials Research Laboratory, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Jungyup LeeFrederick Seitz Materials Research Laboratory, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.ORCID http://orcid.org/0000-0001-9432-5217
Zhaoqian XieDepartment of Materials Science and Engineering, Northwestern University, Evanston, IL 60208, USA.ORCID http://orcid.org/0000-0003-1320-817X
Erin M IblerDepartment of Dermatology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
KunHyuck LeeSimpson Querrey Institute, Northwestern University, Chicago, IL 60611, USA.
Anthony BanksSimpson Querrey Institute, Northwestern University, Chicago, IL 60611, USA.ORCID http://orcid.org/0000-0002-0509-0370
Ji Yoon JeongFrederick Seitz Materials Research Laboratory, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.ORCID http://orcid.org/0000-0001-7034-9855
Jongwon KimDepartment of Materials Science and Engineering, Northwestern University, Evanston, IL 60208, USA.ORCID http://orcid.org/0000-0003-0090-6243
Christopher OgleSimpson Querrey Institute, Northwestern University, Chicago, IL 60611, USA.
Dominic GrandeFrederick Seitz Materials Research Laboratory, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.ORCID http://orcid.org/0000-0002-1346-2373
Yongjoon YuFrederick Seitz Materials Research Laboratory, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.ORCID http://orcid.org/0000-0003-0142-1600
Hokyung JangFrederick Seitz Materials Research Laboratory, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Pourya AssemDepartment of Electrical and Computer Engineering, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.ORCID http://orcid.org/0000-0002-4439-5134
Dennis RyuSimpson Querrey Institute, Northwestern University, Chicago, IL 60611, USA.
Jean Won KwakSimpson Querrey Institute, Northwestern University, Chicago, IL 60611, USA.ORCID http://orcid.org/0000-0001-7883-9242
Myeong NamkoongSimpson Querrey Institute, Northwestern University, Chicago, IL 60611, USA.ORCID http://orcid.org/0000-0002-9209-7721
Jun Bin ParkFrederick Seitz Materials Research Laboratory, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.ORCID http://orcid.org/0000-0002-7818-9697
Yechan LeeFrederick Seitz Materials Research Laboratory, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.ORCID http://orcid.org/0000-0002-4744-267X
Do Hoon KimFrederick Seitz Materials Research Laboratory, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.ORCID http://orcid.org/0000-0002-7187-3306
Arin RyuFrederick Seitz Materials Research Laboratory, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.ORCID http://orcid.org/0000-0001-9950-6738
Jaeseok JeongFrederick Seitz Materials Research Laboratory, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Kevin YouFrederick Seitz Materials Research Laboratory, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.ORCID http://orcid.org/0000-0002-1985-4036
Bowen JiDepartment of Materials Science and Engineering, Northwestern University, Evanston, IL 60208, USA.ORCID http://orcid.org/0000-0002-2655-4840
Zhuangjian LiuInstitute of High Performance Computing, A*Star, 138632 Singapore.
Qingze HuoDepartment of Materials Science and Engineering, Northwestern University, Evanston, IL 60208, USA.
Xue FengApplied Mechanics Laboratory, Department of Engineering Mechanics, Center for Mechanics and Materials, Center for Flexible Electronics Technology, Tsinghua University, Beijing 100084, China.ORCID http://orcid.org/0000-0001-9242-8474
Yujun DengDepartment of Civil and Environmental Engineering, Northwestern University, Evanston, IL 60208, USA.
Yeshou XuDepartment of Civil and Environmental Engineering, Northwestern University, Evanston, IL 60208, USA.
Kyung-In JangDepartment of Robotics Engineering, Daegu Gyeongbuk Institute of Science and Technology (DGIST), Daegu 42988, Republic of Korea.ORCID http://orcid.org/0000-0002-4664-5029
Jeonghyun KimDepartment of Electronics Convergence Engineering, Kwangwoon University, Seoul 01897, Republic of Korea.ORCID http://orcid.org/0000-0003-3090-1435
Yihui ZhangApplied Mechanics Laboratory, Department of Engineering Mechanics, Center for Mechanics and Materials, Center for Flexible Electronics Technology, Tsinghua University, Beijing 100084, China.ORCID http://orcid.org/0000-0003-0885-2067
Roozbeh GhaffariSimpson Querrey Institute, Northwestern University, Chicago, IL 60611, USA.
Casey M RandCenter for Autonomic Medicine, Department of Pediatrics, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL 60611, USA.
Molly SchauDivision of Neonatology, Department of Pediatrics, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL 60611, USA.
Aaron HamvasStanley Manne Children's Research Institute, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL 60611, USA.ORCID http://orcid.org/0000-0002-5749-7797
Debra E Weese-MayerCenter for Autonomic Medicine, Department of Pediatrics, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL 60611, USA.
Yonggang HuangDepartment of Materials Science and Engineering, Northwestern University, Evanston, IL 60208, USA.ORCID http://orcid.org/0000-0002-0483-8359
Seung Min LeeDepartment of Energy Electronics Convergence, Kookmin University, Seoul 02707, Republic of Korea.
Chi Hwan LeeWeldon School of Biomedical Engineering, School of Mechanical Engineering, Center for Implantable Devices, and Birck Nanotechnology Center, Purdue University, West Lafayette, IN 47907, USA.ORCID http://orcid.org/0000-0002-4868-7054
Naresh R ShanbhagDepartment of Electrical and Computer Engineering, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.ORCID http://orcid.org/0000-0002-4323-9164
Amy S PallerCenter for Bio-integrated Electronics, Northwestern University, Evanston, IL 60208, USA. apaller@northwestern.edu stevexu@northwestern.edu jrogers@northwestern.edu.ORCID http://orcid.org/0000-0001-6187-6549
Shuai XuSimpson Querrey Institute, Northwestern University, Chicago, IL 60611, USA. apaller@northwestern.edu stevexu@northwestern.edu jrogers@northwestern.edu.
John A RogersSimpson Querrey Institute, Northwestern University, Chicago, IL 60611, USA. apaller@northwestern.edu stevexu@northwestern.edu jrogers@northwestern.edu.ORCID http://orcid.org/0000-0002-3830-5980

Funding

Northwestern University Clinical and Translational Science Institute (NUCATS)UL1TR001422 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI D'AQUILA, RICHARD · 2015 to 2023
$56.8M
NCATS NIH HHS UL1 TR001422
6 · The paper itself

Abstract

Existing vital sign monitoring systems in the neonatal intensive care unit (NICU) require multiple wires connected to rigid sensors with strongly adherent interfaces to the skin. We introduce a pair of ultrathin, soft, skin-like electronic devices whose coordinated, wireless operation reproduces the functionality of these traditional technologies but bypasses their intrinsic limitations. The enabling advances in engineering science include designs that support wireless, battery-free operation; real-time, in-sensor data analytics; time-synchronized, continuous data streaming; soft mechanics and gentle adhesive interfaces to the skin; and compatibility with visual inspection and with medical imaging techniques used in the NICU. Preliminary studies on neonates admitted to operating NICUs demonstrate performance comparable to the most advanced clinical-standard monitoring systems.

Indexed as

Intensive Care, NeonatalDiagnostic ImagingElectronicsEquipment DesignHumansInfant, NewbornLab-On-A-Chip DevicesMonitoring, PhysiologicSkinVital SignsWireless Technology

Identifiers

PMID30819934
PMCPMC6510306

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.