Evidence map›Paper›PMID 30819916›Full record

ArticleHaematologica2019

A B-cell receptor-related gene signature predicts response to ibrutinib treatment in mantle cell lymphoma cell lines.

Tiziana D'Agaro, Antonella Zucchetto, Filippo Vit, Tamara Bittolo, Erika Tissino, Francesca Maria Rossi, Massimo Degan, Francesco Zaja, Pietro Bulian, Michele Dal Bo and 5 more

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Haematologica, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Tiziana D'AgaroClinical and Experimental Onco-Hematology Unit, Centro di Riferimento Oncologico di Aviano (CRO), IRCCS, Aviano.
Antonella ZucchettoClinical and Experimental Onco-Hematology Unit, Centro di Riferimento Oncologico di Aviano (CRO), IRCCS, Aviano.
Filippo VitClinical and Experimental Onco-Hematology Unit, Centro di Riferimento Oncologico di Aviano (CRO), IRCCS, Aviano.
Tamara BittoloClinical and Experimental Onco-Hematology Unit, Centro di Riferimento Oncologico di Aviano (CRO), IRCCS, Aviano.
Erika TissinoClinical and Experimental Onco-Hematology Unit, Centro di Riferimento Oncologico di Aviano (CRO), IRCCS, Aviano.
Francesca Maria RossiClinical and Experimental Onco-Hematology Unit, Centro di Riferimento Oncologico di Aviano (CRO), IRCCS, Aviano.
Massimo DeganClinical and Experimental Onco-Hematology Unit, Centro di Riferimento Oncologico di Aviano (CRO), IRCCS, Aviano.
Francesco ZajaDepartment of Internal Medicine and Haematology, Maggiore General Hospital, University of Trieste, Trieste.
Pietro BulianClinical and Experimental Onco-Hematology Unit, Centro di Riferimento Oncologico di Aviano (CRO), IRCCS, Aviano.
Michele Dal BoClinical and Experimental Onco-Hematology Unit, Centro di Riferimento Oncologico di Aviano (CRO), IRCCS, Aviano.
Simone FerreroDepartment of Molecular Biotechnologies and Health Sciences, Hematology Division 1, University of Torino, Torino.
Marco LadettoDepartment of Molecular Biotechnologies and Health Sciences, Hematology Division 1, University of Torino, Torino.
Alberto ZamòDepartment of Oncology, University of Torino, Torino, Italy.
Valter GatteiClinical and Experimental Onco-Hematology Unit, Centro di Riferimento Oncologico di Aviano (CRO), IRCCS, Aviano.
Riccardo BombenClinical and Experimental Onco-Hematology Unit, Centro di Riferimento Oncologico di Aviano (CRO), IRCCS, Aviano rbomben@cro.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Gene Expression ProfilingAdenineAgammaglobulinaemia Tyrosine KinaseAntineoplastic AgentsBiomarkers, TumorCD79 AntigensCell Line, TumorClass I Phosphatidylinositol 3-KinasesGene Expression Regulation, NeoplasticHumansImmunotherapyLeukocytes, MononuclearLymphoma, Mantle-CellNeoplasm Recurrence, LocalPiperidinesPrognosisAdenineAgammaglobulinaemia Tyrosine KinaseAKT3 protein, humanAntineoplastic AgentsBCL2 protein, humanBiomarkers, TumorBTK protein, humanCD79 AntigensCD79B protein, humanClass I Phosphatidylinositol 3-KinasesibrutinibPIK3CD protein, humanPiperidinesProto-Oncogene Proteins c-aktProto-Oncogene Proteins c-bcl-2PyrazolesPyrimidinesReceptors, Antigen, B-CellSyk KinaseSYK protein, human

Identifiers

PMID30819916
PMCPMC6717584

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.