Evidence map›Paper›PMID 30819913›Full record

ArticleHaematologica2019

Dynamic prediction of bleeding risk in thrombocytopenic preterm neonates.

Susanna F Fustolo-Gunnink, Karin Fijnvandraat, Hein Putter, Isabelle M Ree, Camila Caram-Deelder, Peter Andriessen, Esther J d'Haens, Christian V Hulzebos, Wes Onland, André A Kroon and 3 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Haematologica, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06043050 (Sequential Predictions Under Repeated Interventions), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06043050 completednot on this mapstarted 2022, after this paper: background citation

Sequential Predictions Under Repeated Interventions: Estimating the Risk of Major Bleeding or Death With and Without Prophylactic Platelet Transfusion in Thrombocytopenic Neonates.

TypeobservationalSponsorLeiden University Medical CenterRan2022 to 2024Enrolled1,042ConditionsNeonatal Thrombocytopenia, Intraventricular Hemorrhage, Platelet TransfusionArmsPlatelets
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 25 citations in OpenAlex.

  1. Trial
  2. Observational
  3. Article
  4. Observational
  5. Article
  6. Article
  7. Review
  8. Hemostatic Challenges in Neonates.Frontiers in pediatrics · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 9 institutions in 2 countries.

Susanna F Fustolo-GunninkSanquin/LUMC, Center for Clinical Transfusion Research, Leiden.
Karin FijnvandraatAmsterdam University Medical Center, Emma Children's Hospital, Department of Pediatric Hematology, Amsterdam-Zuidoost.
Hein PutterLeiden University Medical Center, Department of Medical Statistics, Leiden.
Isabelle M ReeLeiden University Medical Center, Willem Alexander Children's Hospital, Department of Neonatology, Leiden.
Camila Caram-DeelderSanquin/LUMC, Center for Clinical Transfusion Research, Leiden.
Peter AndriessenMáxima Medical Center, Department of Neonatology, Veldhoven.
Esther J d'HaensIsala Zwolle, Amalia Children's Center, Department of Neonatology, Zwolle.
Christian V HulzebosUniversity Medical Center Groningen, Beatrix Children's Hospital, Department of Neonatology, Groningen.
Wes OnlandAmsterdam University Medical Center, Emma Children's Hospital, Department of Neonatology, Amsterdam-Zuidoost.
André A KroonErasmus Medical Center, Sophia Children's Hospital, Department of Neonatology, Rotterdam.
Daniël C VijlbriefUniversity Medical Center Utrecht, Utrecht University, Wilhelmina Children's Hospital, Department of Neonatology, Utrecht.
Enrico LoprioreLeiden University Medical Center, Willem Alexander Children's Hospital, Department of Neonatology, Leiden.
Johanna G van der BomSanquin/LUMC, Center for Clinical Transfusion Research, Leiden j.g.vanderbom@lumc.nl.
Leiden University Medical Center · NLSanquin · NLChildren's Center · USEmma Kinderziekenhuis · NLErasmus MC - Sophia Children’s Hospital · NLMáxima Medisch Centrum · NLUniversity Medical Center · USUniversity Medical Center Groningen · NLUtrecht University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Over 75% of severely thrombocytopenic neonates receive platelet transfusions, though little evidence supports this practice, and only 10% develop major bleeding. In a recent randomized trial, giving platelet transfusions at a threshold platelet count of 50x10

Indexed as

Infant, PrematureBiomarkersDisease ManagementHemorrhageHumansInfant, NewbornModels, StatisticalPlatelet CountPrognosisReproducibility of ResultsThrombocytopeniaBiomarkers

Identifiers

PMID30819913
PMCPMC6821634
OpenAlexW2918455775

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.