Evidence map›Paper›PMID 30819892›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2019

Regulatory changes in pterin and carotenoid genes underlie balanced color polymorphisms in the wall lizard.

Pedro Andrade, Catarina Pinho, Guillem Pérez I de Lanuza, Sandra Afonso, Jindřich Brejcha, Carl-Johan Rubin, Ola Wallerman, Paulo Pereira, Stephen J Sabatino, Adriana Bellati and 14 more

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 104 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
104citing papers in PubMed, 2 pooled it
45.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

104 citing papers in PubMed, 2 syntheses or guidelines pooled it, 242 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  11. A century of theories of balancing selection.Biological reviews of the Cambridge Philosophical Society · 2026
    Review
  12. Cell type diversification and phenotype convergence underlying white fin-ornamentation of cyprinid fishes.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  13. A Loss-of-Function Mutation inAnimals : an open access journal from MDPI · 2026
    Article
  14. Article
  15. Article
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  17. Cryptic Ontogenetic Changes in the Ventral Coloration of a Color Polymorphic Wall Lizard (Podarcis muralis).Journal of experimental zoology. Part A, Ecological and integrative physiology · 2026
    Article
  18. Article
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44 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 9 institutions in 8 countries.

Pedro AndradeCIBIO/InBIO, Centro de Investigação em Biodiversidade e Recursos Genéticos, Universidade do Porto, 4485-661 Vairão, Portugal.
Catarina PinhoCIBIO/InBIO, Centro de Investigação em Biodiversidade e Recursos Genéticos, Universidade do Porto, 4485-661 Vairão, Portugal.
Guillem Pérez I de LanuzaCIBIO/InBIO, Centro de Investigação em Biodiversidade e Recursos Genéticos, Universidade do Porto, 4485-661 Vairão, Portugal.
Sandra AfonsoCIBIO/InBIO, Centro de Investigação em Biodiversidade e Recursos Genéticos, Universidade do Porto, 4485-661 Vairão, Portugal.ORCID 0000-0001-7212-991X
Jindřich BrejchaDepartment of Philosophy and History of Science, Faculty of Science, Charles University, 128 00 Prague 2, Czech Republic.
Carl-Johan RubinScience for Life Laboratory Uppsala, Department of Medical Biochemistry and Microbiology, Uppsala University, 752 36 Uppsala, Sweden.
Ola WallermanScience for Life Laboratory Uppsala, Department of Medical Biochemistry and Microbiology, Uppsala University, 752 36 Uppsala, Sweden.
Paulo PereiraCIBIO/InBIO, Centro de Investigação em Biodiversidade e Recursos Genéticos, Universidade do Porto, 4485-661 Vairão, Portugal.
Stephen J SabatinoCIBIO/InBIO, Centro de Investigação em Biodiversidade e Recursos Genéticos, Universidade do Porto, 4485-661 Vairão, Portugal.
Adriana BellatiDepartment of Earth and Environmental Sciences, University of Pavia, 27100 Pavia, Italy.
Daniele Pellitteri-RosaDepartment of Earth and Environmental Sciences, University of Pavia, 27100 Pavia, Italy.
Zuzana BosakovaDepartment of Analytical Chemistry, Faculty of Science, Charles University, 128 43 Prague 2, Czech Republic.
Ignas BunikisScience for Life Laboratory Uppsala, Department of Immunology, Genetics and Pathology, Uppsala University, 752 36 Uppsala, Sweden.
Miguel A CarreteroCIBIO/InBIO, Centro de Investigação em Biodiversidade e Recursos Genéticos, Universidade do Porto, 4485-661 Vairão, Portugal.
Nathalie FeinerDepartment of Biology, Lund University, 223 62 Lund, Sweden.
Petr MarsikDepartment of Food Science, Faculty of Agrobiology, Food and Natural Resources, Czech University of Life Sciences Prague, 165 21 Prague 6, Czech Republic.
Francisco PaupérioDepartamento de Biologia, Faculdade de Ciências, Universidade do Porto, 4169-007 Porto, Portugal.
Daniele SalviCIBIO/InBIO, Centro de Investigação em Biodiversidade e Recursos Genéticos, Universidade do Porto, 4485-661 Vairão, Portugal.ORCID 0000-0002-3804-2690
Lucile SolerScience for Life Laboratory, National Bioinformatics Infrastructure Sweden (NBIS), 751 23 Uppsala, Sweden.ORCID 0000-0002-0121-2393
Geoffrey M WhileSchool of Biological Sciences, University of Tasmania, Hobart, TAS 7005 Tasmania, Australia.
Tobias UllerDepartment of Biology, Lund University, 223 62 Lund, Sweden.
Enrique FontEthology Laboratory, Cavanilles Institute of Biodiversity and Evolutionary Biology, University of Valencia, 469 80 Paterna, Spain.
Leif AnderssonScience for Life Laboratory Uppsala, Department of Medical Biochemistry and Microbiology, Uppsala University, 752 36 Uppsala, Sweden; leif.andersson@imbim.uu.se miguel.carneiro@cibio.up.pt.ORCID 0000-0002-4085-6968
Miguel CarneiroCIBIO/InBIO, Centro de Investigação em Biodiversidade e Recursos Genéticos, Universidade do Porto, 4485-661 Vairão, Portugal; leif.andersson@imbim.uu.se miguel.carneiro@cibio.up.pt.
Universidade do Porto · PTUppsala University · SECharles University · CZLund University · SEUniversity of Pavia · ITCzech University of Life Sciences Prague · CZParc Científic de la Universitat de València · ESScience for Life Laboratory · SEUniversity of Tasmania · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reptiles use pterin and carotenoid pigments to produce yellow, orange, and red colors. These conspicuous colors serve a diversity of signaling functions, but their molecular basis remains unresolved. Here, we show that the genomes of sympatric color morphs of the European common wall lizard (

Indexed as

Alcohol OxidoreductasesAnimalsCarotenoidsColorDioxygenasesLizardsPigmentationPolymorphism, GeneticPterinsSkin PigmentationAlcohol OxidoreductasesCarotenoidsDioxygenasesPterinssepiapterin reductasebalanced polymorphismcarotenoid pigmentationintrogressionPodarcis muralispterin pigmentation

Identifiers

PMID30819892
PMCPMC6431182
OpenAlexW2902590891

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.