Evidence map›Paper›PMID 30819890›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2019

Human cytomegalovirus haplotype reconstruction reveals high diversity due to superinfection and evidence of within-host recombination.

Juliana Cudini, Sunando Roy, Charlotte J Houldcroft, Josephine M Bryant, Daniel P Depledge, Helena Tutill, Paul Veys, Rachel Williams, Austen J J Worth, Asif U Tamuri and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 81 papers.

0numbers the graph read from it
0cells of the map it votes in
81citing papers in PubMed
13.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

81 citing papers in PubMed, 122 citations in OpenAlex.

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  18. The Pentamer glycoprotein complex inhibits viral Immediate Early transcription during Human Cytomegalovirus infections.Proceedings of the National Academy of Sciences of the United States of America · 2024
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21 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Juliana CudiniDivision of Infection and Immunity, University College London, London WC1E 6BT, United Kingdom.
Sunando RoyDivision of Infection and Immunity, University College London, London WC1E 6BT, United Kingdom.
Charlotte J HouldcroftInfection, Immunity, Inflammation and Physiological Medicine, Institute of Child Health, University College London, London WC1N 1EH, United Kingdom.
Josephine M BryantDivision of Infection and Immunity, University College London, London WC1E 6BT, United Kingdom.
Daniel P DepledgeDivision of Infection and Immunity, University College London, London WC1E 6BT, United Kingdom.
Helena TutillDivision of Infection and Immunity, University College London, London WC1E 6BT, United Kingdom.
Paul VeysGreat Ormond Street Hospital for Children, London WC1N 3JH, United Kingdom.
Rachel WilliamsDivision of Infection and Immunity, University College London, London WC1E 6BT, United Kingdom.
Austen J J WorthGreat Ormond Street Hospital for Children, London WC1N 3JH, United Kingdom.
Asif U TamuriResearch Computing, University College London, London WC1E 6BT, United Kingdom.
Richard A GoldsteinDivision of Infection and Immunity, University College London, London WC1E 6BT, United Kingdom; r.goldstein@ucl.ac.uk j.breuer@ucl.ac.uk.ORCID 0000-0001-5148-4672
Judith BreuerDivision of Infection and Immunity, University College London, London WC1E 6BT, United Kingdom; r.goldstein@ucl.ac.uk j.breuer@ucl.ac.uk.ORCID 0000-0001-8246-0534
University College London · GBGreat Ormond Street Hospital · GB

Funding

Biotechnology and Biological Sciences Research Council BB/P007562/1
6 · The paper itself

Abstract

Recent sequencing efforts have led to estimates of human cytomegalovirus (HCMV) genome-wide intrahost diversity that rival those of persistent RNA viruses [Renzette N, Bhattacharjee B, Jensen JD, Gibson L, Kowalik TF (2011)

Indexed as

Base SequenceChildChild, PreschoolCytomegalovirusCytomegalovirus InfectionsDNA, ViralFemaleGenetic VariationGenome, HumanGenome, ViralHaplotypesHigh-Throughput Nucleotide SequencingHumansImmunocompromised HostInfantInfant, NewbornDNA, Viraldiversityhuman cytomegalovirusrecombinationsuperinfectionwhole genome sequencing

Identifiers

PMID30819890
PMCPMC6431178
OpenAlexW2920531118

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.