Evidence map›Paper›PMID 30819706›Full record

SynthesisBMJ open2019

Addressing cognitive impairment following stroke: systematic review and meta-analysis of non-randomised controlled studies of psychological interventions.

Niamh A Merriman, Eithne Sexton, Grainne McCabe, Mary E Walsh, Daniela Rohde, Ashleigh Gorman, Isabelle Jeffares, Nora-Ann Donnelly, Niall Pender, David J Williams and 5 more

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
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  4. Cognitive rehabilitation for attention deficits following stroke.The Cochrane database of systematic reviews · 2019
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  19. Memory rehabilitation during the COVID-19 pandemic.BMC medical informatics and decision making · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Niamh A MerrimanDivision of Population Health Sciences, Royal College of Surgeons in Ireland, Dublin, Ireland.ORCID 0000-0002-5327-7762
Eithne SextonDivision of Population Health Sciences, Royal College of Surgeons in Ireland, Dublin, Ireland.
Grainne McCabeLibrary, Royal College of Surgeons in Ireland, Dublin, Ireland.
Mary E WalshDivision of Population Health Sciences, Royal College of Surgeons in Ireland, Dublin, Ireland.
Daniela RohdeDivision of Population Health Sciences, Royal College of Surgeons in Ireland, Dublin, Ireland.ORCID 0000-0001-8834-2539
Ashleigh GormanDivision of Population Health Sciences, Royal College of Surgeons in Ireland, Dublin, Ireland.
Isabelle JeffaresDivision of Population Health Sciences, Royal College of Surgeons in Ireland, Dublin, Ireland.
Nora-Ann DonnellySocial Research Division, Economic and Social Research Institute, Dublin, Ireland.
Niall PenderDepartment of Psychology, Beaumont Hospital, Dublin, Ireland.
David J WilliamsDepartment of Geriatric and Stroke Medicine, Beaumont Hospital, Dublin, Ireland.
Frances HorganSchool of Physiotherapy, Royal College of Surgeons in Ireland, Dublin, Ireland.
Frank DoyleDivision of Population Health Sciences, Royal College of Surgeons in Ireland, Dublin, Ireland.
Maev-Ann WrenSocial Research Division, Economic and Social Research Institute, Dublin, Ireland.
Kathleen E BennettDivision of Population Health Sciences, Royal College of Surgeons in Ireland, Dublin, Ireland.
Anne HickeyDivision of Population Health Sciences, Royal College of Surgeons in Ireland, Dublin, Ireland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveCognitive impairment is a pervasive outcome of stroke, reported in over half of patients 6 months post-stroke and is associated with increased disability and a poorer quality of life. Despite the prevalence of post-stroke cognitive impairment, the efficacy of existing psychological interventions for the rehabilitation of cognitive impairment following stroke has yet to be established. The aim of this study is to identify psychological interventions from non-randomised studies that intended to improve post-stroke cognitive function and establish their efficacy.

designSystematic review and meta-analysis of non-randomised studies of psychological interventions addressing post-stroke cognitive impairment. DATA SOURCES: Electronic searches were performed in the Pubmed, EMBASE and PsycINFO databases, the search dating from inception to February 2017. ELIGIBILITY CRITERIA: All non-randomised controlled studies and quasi-randomised controlled trials examining psychological interventions to improve cognitive function following stroke were included, such as feasibility studies, pilot studies, experimental studies, and quasi-experimental studies. The primary outcome was cognitive function. The prespecified secondary outcomes were functional abilities in daily life and quality of life.

methodsThe current meta-analyses combined the findings of seven controlled studies, examining the efficacy of psychological interventions compared with treatment-as-usual controls or active controls, and 13 one-group pre-post studies.

resultsResults indicated an overall small effect on cognition across the controlled studies (Hedges' g=0.38, 95% CI=0.06 to 0.7) and a moderate effect on cognition across the one-group pre-post studies (Hedges' g=0.51, 95% CI=0.3 to 0.73). Specific cognitive domains, such as memory and attention also demonstrated a benefit of psychological interventions.

conclusionsThis review provides support for the potential of psychological interventions to improve overall cognitive function post-stroke. Limitations of the study, in terms of risk of bias and quality of included studies, and future research directions are explored. PROSPERO REGISTRATION NUMBER: CRD42017069714.

Indexed as

Cognitive DysfunctionHumansPsychotherapyStrokecognitive impairmentcognitive rehabilitationmeta-analysisstrokesystematic review

Identifiers

PMID30819706
PMCPMC6398645

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.