Evidence map›Paper›PMID 30819685›Full record

ArticleBMJ (Clinical research ed.)2019

Pre-hospital advanced airway management for adults with out-of-hospital cardiac arrest: nationwide cohort study.

Junichi Izawa, Sho Komukai, Koichiro Gibo, Masashi Okubo, Kosuke Kiyohara, Chika Nishiyama, Takeyuki Kiguchi, Tasuku Matsuyama, Takashi Kawamura, Taku Iwami and 2 more

Open access · hybridAbstract read
In one paragraph

Article in BMJ (Clinical research ed.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
12.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 93 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 2 countries.

Junichi IzawaDepartment of Anesthesiology, The Jikei University School of Medicine, Tokyo 105-8491, Japan izawa.junichi.87r@st.kyoto-u.ac.jp.ORCID http://orcid.org/0000-0003-1920-8218
Sho KomukaiDivision of Biomedical Statistics, Department of Integrated Medicine, Graduate School of Medicine, Osaka University, Osaka, Japan.
Koichiro GiboDepartment of Emergency Medicine, Okinawa Chubu Hospital, Okinawa, Japan.
Masashi OkuboDepartment of Emergency Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
Kosuke KiyoharaDepartment of Food Science, Otsuma Women's University, Tokyo, Japan.
Chika NishiyamaDepartment of Critical Care Nursing, Kyoto University Graduate School of Human Health Science, Kyoto, Japan.
Takeyuki KiguchiKyoto University Health Service, Kyoto, Japan.
Tasuku MatsuyamaDepartment of Emergency Medicine, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Takashi KawamuraKyoto University Health Service, Kyoto, Japan.
Taku IwamiKyoto University Health Service, Kyoto, Japan.
Clifton W CallawayDepartment of Emergency Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
Tetsuhisa KitamuraDivision of Environmental Medicine and Population Sciences, Department of Social and Environmental Medicine, Graduate School of Medicine, Osaka University, Osaka, Japan.
Kyoto University · JPThe University of Osaka · JPUniversity of Pittsburgh · USJikei University School of Medicine · JPKyoto Prefectural University of Medicine · JPOkinawa Prefectural Chubu Hospital · JPOtsuma Women's University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine survival associated with advanced airway management (AAM) compared with no AAM for adults with out-of-hospital cardiac arrest.

designCohort study between January 2014 and December 2016.

settingNationwide, population based registry in Japan (All-Japan Utstein Registry).

participantsConsecutive adult patients with out-of-hospital cardiac arrest, separated into two sub-cohorts by their first documented electrocardiographic rhythm: shockable (ventricular fibrillation or pulseless ventricular tachycardia) and non-shockable (pulseless electrical activity or asystole). Patients who received AAM during cardiopulmonary resuscitation were sequentially matched with patients at risk of AAM within the same minute on the basis of time dependent propensity scores.

main outcome measuresSurvival at one month or at hospital discharge within one month.

resultsOf the 310 620 patients eligible, 8459 (41.2%) of 20 516 in the shockable cohort and 121 890 (42.0%) of 290 104 in the non-shockable cohort received AAM during cardiopulmonary resuscitation. After time dependent propensity score sequential matching, 16 114 patients in the shockable cohort and 236 042 in the non-shockable cohort were matched at the same minute. In the shockable cohort, survival did not differ between patients with AAM and those with no AAM: 1546/8057 (19.2%) versus 1500/8057 (18.6%) (adjusted risk ratio 1.00, 95% confidence interval 0.93 to 1.07). In the non-shockable cohort, patients with AAM had better survival than those with no AAM: 2696/118 021 (2.3%) versus 2127/118 021 (1.8%) (adjusted risk ratio 1.27, 1.20 to 1.35).

conclusionsIn the time dependent propensity score sequential matching for out-of-hospital cardiac arrest in adults, AAM was not associated with survival among patients with shockable rhythm, whereas AAM was associated with better survival among patients with non-shockable rhythm.

Indexed as

AdultAgedAirway ManagementCardiopulmonary ResuscitationCohort StudiesElectric CountershockEmergency Medical ServicesFemaleHumansJapanMaleMiddle AgedOdds RatioOut-of-Hospital Cardiac ArrestPatient DischargePropensity Score

Identifiers

PMID30819685
PMCPMC6393774
OpenAlexW2915648932

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.