ArticleTicks and tick-borne diseases2019
Isolation of known and potentially pathogenic tick-borne microorganisms from European ixodid ticks using tick cell lines.
Article in Ticks and tick-borne diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 25 citations in OpenAlex.
- Stenotrophomonas maltophilia in a Rhipicephalus linnaei tick cell culture: detection, antibiotic resistance and multi-locus sequence typing.Antonie van Leeuwenhoek · 2026Article
- A human-associatediScience · 2026Article
- Multicenter Retrospective Study of Spiroplasma ixodetis Infantile Cataract in 8 Countries in Europe.Emerging infectious diseases · 2025Article
- Molecular Profiling of Ticks and Associated Pathogens: First Report ofTransboundary and emerging diseases · 2025Article
- High-Throughput Sequencing Reveals Three Rhabdoviruses Persisting in the IRE/CTVM19 Cell Line.Viruses · 2024Article
- Molecular Survey ofVeterinary sciences · 2023Article
- The Troublesome Ticks Research Protocol: Developing a Comprehensive, Multidiscipline Research Plan for Investigating Human Tick-Associated Disease in Australia.Pathogens (Basel, Switzerland) · 2022Article
- New Cell Lines Derived from European Tick Species.Microorganisms · 2022Article
- Old zoonotic agents and novel variants of tick-borne microorganisms from Benguela (Angola), July 2017.Parasites & vectors · 2022Article
- Article
- Isolation in Natural Host Cell Lines ofInsects · 2021Article
- Replication Kinetics ofMicroorganisms · 2021Article
- Bacterial Pathogens and Symbionts Harboured byPathogens (Basel, Switzerland) · 2021Article
- Article
- Article
- Isolation of Candidatus Rickettsia vini from Belgian Ixodes arboricola ticks and propagation in tick cell lines.Ticks and tick-borne diseases · 2020Article
- Isolation and partial characterisation of a novel Trypanosoma from the tick Ixodes ricinus.Ticks and tick-borne diseases · 2020Article
- Isolation and Propagation of Laboratory Strains and a Novel Flea-Derived Field Strain ofMicroorganisms · 2020Article
- How relevant are in vitro culture models for study of tick-pathogen interactions?Pathogens and global healthReview
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Authors and funding
7 authors at 4 institutions in 4 countries.
Funding
Abstract
Ticks harbour and, in many cases transmit to their vertebrate hosts, a wide variety of pathogenic, apathogenic and endosymbiotic microorganisms. Recent molecular analyses have greatly increased the range of bacterial species potentially associated with ticks, but in most cases cannot distinguish between surface contaminants, microorganisms present in the remains of the previous blood meal and truly intracellular or tissue-associated bacteria. Here we demonstrate how tick cell lines, primary cell cultures and organ cultures can be used to isolate and propagate bacteria from within embryonic and adult Ixodes ricinus, Dermacentor marginatus and Dermacentor reticulatus ticks originating from different parts of Europe. We isolated and partially characterised four new strains of Spiroplasma from The Netherlands, Spain and Poland, two new strains of Rickettsia raoultii from Russia and Poland, one strain of Rickettsia slovaca from Spain and a species of Mycobacterium from the UK. Comparison with published sequences showed that the Spiroplasma strains were closely related to Spiroplasma ixodetis and the Mycobacterium isolate belonged to the Mycobacterium chelonae complex, while the R. raoultii and R. slovaca strains were similar to previously-validated species.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.