Evidence map›Paper›PMID 30819147›Full record

ArticleBMC pregnancy and childbirth2019

Option B plus antiretroviral therapy adherence and associated factors among HIV positive pregnant women in Southern Ethiopia.

Dawit Jember Tesfaye, Desalegn Tsegaw Hibistu, Teshome Abuka Abebo, Feleke Tafesse Asfaw, Kaleegziabher Lukas, Tariku Laelago, Ermias Abera Turuse, Henok Gebreyohaness Kebede, Abraham Abate Altaye, Fanuel Belayneh Bekele

Open access · goldAbstract read
In one paragraph

Article in BMC pregnancy and childbirth, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 3 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 3 syntheses or guidelines pooled it, 26 citations in OpenAlex.

  1. Pooled it
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  10. Level of quality of option BBMC health services research · 2020
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  13. Adherence to Option BHIV/AIDS (Auckland, N.Z.) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Dawit Jember TesfayeDepartment of Epidemiology, School of Public Health, College of Medicine and Health Sciences, Hawassa University, Hawassa, Ethiopia. devanhijember@gmail.com.ORCID http://orcid.org/0000-0003-3831-5465
Desalegn Tsegaw HibistuDepartment of Reproductive Health, School of Public Health, College of Medicine and Health Sciences, Hawassa University, Hawassa, Ethiopia.
Teshome Abuka AbeboDepartment of Reproductive Health, School of Public Health, College of Medicine and Health Sciences, Hawassa University, Hawassa, Ethiopia.
Feleke Tafesse AsfawDepartment of Health Service Management, School of Public Health, College of Medicine and Health Sciences, Hawassa University, Hawassa, Ethiopia.
Kaleegziabher LukasCollege of Medicine and Health Sciences, Wachemo University, Hossana, Ethiopia.
Tariku LaelagoHossana College of Health Sciences, Hossana, Ethiopia.
Ermias Abera TuruseCollege of Medicine and Health Sciences, Wachemo University, Hossana, Ethiopia.
Henok Gebreyohaness KebedeYale Global Leadership Institute, Yale School of Public health, YGE-GHLI, New Heaven, Ethiopia.
Abraham Abate AltayeDepartment of Midwifery, Hawassa College of Health Sciences, Hawassa, Ethiopia.
Fanuel Belayneh BekeleDepartment of Epidemiology, School of Public Health, College of Medicine and Health Sciences, Hawassa University, Hawassa, Ethiopia.
Hawassa University · ETWachemo University

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAdherence to Option B plus Antiretroviral Therapy plays a vital role in preventing mother to child transmission of Human Immunodeficiency Virus and development of drug resistance. This study was aimed to assess adherence to option B plus ART and associated factors among HIV positive pregnant women at public Hospitals in Southern Ethiopia.

methodsFacility based cross sectional study was conducted on HIV positive pregnant mothers attending public health facilities' antenatal care unit. Systematic random sampling technique was employed to select 290 HIV positive pregnant women enrolled in the Option B plus program. Data were collected by using structured questionnaire. Bivariate and multivariable logistic regression analysis were used to identify factors associated with option B plus ART adherence. P-value less than 0.05 was considered as cut of point to declare statistical significance.

resultsThe overall adherence to option B plus ART among HIV positive pregnant women was 236 (81.4%). Three in twenty, (14.8%) participants were none adherent to Option B plus ART due to difficulty in adopting time schedule and forgetting to take medication. During first trimester of pregnancy, 16 (5.5%) were stopped taking ART medication due to side effects. Pregnant women who started ART at the time of HIV diagnosis [AOR = 1.99, 95% CI: (1.02, 3.95)], and who had five or more antenatal care visits [AOR = 4.10, 95% CI (1.65, 10.02)] were more likely to adhere to option B plus ART. Women who should travel 30-60 min on foot to access ART from service delivering facilities were less likely to adhere to option B plus [AOR = 0.39, 95% C I: (0.17, 0.88)].

conclusionsThe overall adherence to option B plus ART was suboptimal. Measures that improve recalling ability of individuals to take ART on time, and minimize ART side effects during first trimester of pregnancy need to be given emphasis. The study finding indicates the need for reconsidering the ad-hoc focused antenatal care visit at policy and program level by increasing the number of follow up visit with proper counseling on ART adherence benefits, and improving service accessibility.

Indexed as

Drug MonitoringAdolescentAdultAlkynesAnti-HIV AgentsBenzoxazinesCross-Sectional StudiesCyclopropanesDeveloping CountriesDirective CounselingDrug Therapy, CombinationEthiopiaFemaleHealth Services AccessibilityHIV SeropositivityHospitals, PublicAlkynesAnti-HIV AgentsBenzoxazinesCyclopropanesefavirenzLamivudineTenofovirAdherenceAntiretroviral therapyOption B plusPregnant women

Identifiers

PMID30819147
PMCPMC6394094
OpenAlexW2931360756

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.