ArticleBMC neurology2019
Treatment patterns and burden of behavioral disturbances in patients with dementia in the United States: a claims database analysis.
Article in BMC neurology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
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Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Predictive models of Alzheimer's disease dementia risk in older adults with mild cognitive impairment: a systematic review and critical appraisal.BMC geriatrics · 2024Pooled it
- Health Care Team Interventions to Reduce Distress Behaviors in Older Adults: A Systematic Review.Clinical gerontologistPooled it
- Physician Antipsychotic Overprescribing Letters and Cognitive, Behavioral, and Physical Health Outcomes Among People With Dementia: A Secondary Analysis of a Randomized Clinical Trial.JAMA network open · 2024Trial
- Machine Learning Prediction of One-Year Rehospitalization in Dementia: A Retrospective Cohort Study.Health science reports · 2026Article
- Behavioral and psychological symptoms of dementia and its relationship with caregiver burden: A cross-sectional study of inpatients with dementia in a tertiary center.Indian journal of psychiatry · 2026Article
- Agitation in individuals with Alzheimer's disease: An assessment of behaviors using the cohen-mansfield agitation inventory in community-dwellers and impact on caregiver experience.Dementia (London, England) · 2026Article
- Article
- Ascertaining Out-of-Pocket Costs of Dementia Care: Feasibility Study of a Web-Based Weekly Survey.JMIR formative research · 2024Article
- 2024 Alzheimer's disease facts and figures.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- Healthcare Resource Utilization Among Patients With Agitation in Alzheimer Dementia.Journal of health economics and outcomes research · 2024Article
- Factors Associated With Increased Health Care Utilization for Patients With Dementia With Lewy Bodies: A Narrative Review.Journal of patient-centered research and reviews · 2024Review
- Diagnosis of behavioral symptoms as a predictor of institutionalization among Medicaid patients with dementia.BMC geriatrics · 2023Article
- Economic outcomes associated with diagnosed behavioral symptoms among patients with dementia in the United States: a health care claims database analysis.BMC geriatrics · 2023Observational
- Key gene network related to primary ciliary dyskinesia in hippocampus of patients with Alzheimer's disease revealed by weighted gene co-expression network analysis.BMC neurology · 2022Article
- Economic Evaluation of Healthcare Resource Utilization and Costs for Newly Diagnosed Dementia-Related Psychosis.Geriatrics (Basel, Switzerland) · 2022Article
- Effects of rich cannabidiol oil on behavioral disturbances in patients with dementia: A placebo controlled randomized clinical trial.Frontiers in medicine · 2022Article
- Impact of agitation in long-term care residents with dementia in the United States.International journal of geriatric psychiatry · 2021Article
- Peripheral Leukocytosis Predicts Cognitive Decline but Not Behavioral Disturbances: A Nationwide Study of Alzheimer's and Parkinson's Disease Patients.Dementia and geriatric cognitive disorders · 2021Article
- Medications in Patients with Dementia and Behavioral Disturbance.Journal of Alzheimer's disease reports · 2021Article
- Treatment Patterns of Patients with All-Cause Dementia in Russia.Journal of Alzheimer's disease reports · 2020Article
Corrections and comments
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Authors and funding
5 authors.
Funding
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Abstract
backgroundAlthough patients with dementia frequently experience neuropsychological symptoms (NPS) such as agitation, which profoundly impacts patients, caregivers, and the healthcare system, few studies have evaluated the associated burden of agitation or agitation-related symptoms in dementia.
methodsThis retrospective analysis of claims data from the Truven Health MarketScan® database (2012-2015) compared clinical characteristics, treatment patterns, healthcare resource utilization, and costs among patients with dementia with behavioral disturbances (BD) versus patients with dementia without BD. Existing BD diagnosis codes 294.11 or 294.21 were used as a means to identify patients with agitation/agitation-related symptoms.
resultsFrom a starting sample of 6.4 million beneficiaries, 103,402 patients with dementia were identified, of whom 16,440 (16%) had BD during an average of 17 months of follow-up. Patients with BD had significantly more medical and psychiatric comorbidities and greater comedication use (i.e., antidementia drugs, antidepressants, and antipsychotics; all values, P < .0001) compared with patients without BD. A significantly greater number of hospitalizations, hospital days, outpatient hospital/clinic visits, number of skilled nursing visits, and number of patients with hospice visit were reported during follow-up in patients with BD compared with patients without BD (all values, P < 0.0001). Costs were also significantly higher among patients with BD versus those patients without BD ($42,284 vs. $32,640, respectively; P < 0.0001).
conclusionsPatients with dementia with BD had a higher prevalence of comorbidities, greater use of comedications, and greater healthcare utilization and costs than patients with dementia without BD.
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