Evidence map›Paper›PMID 30819115›Full record

ArticleBMC infectious diseases2019

Implementation and evaluation of an algorithm for the management of scabies outbreaks.

Simon M Mueller, Stefan Gysin, Michael Schweitzer, Simon Schwegler, Peter Haeusermann, Peter Itin, Thomas Bart, Ruth Spieler Denz, Thomas Steffen, Richard Kuehl and 2 more

Open access · goldAbstract read
In one paragraph

Article in BMC infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. [Determinants of asylum seekers' health and medical care in Germany].Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2023
    Review
  5. Scabies outbreak during home confinement due to the SARS-CoV-2 pandemic.Journal of the European Academy of Dermatology and Venereology : JEADV · 2020
    Article
  6. Diagnostic Accuracy of Dermoscopy for Scabies.The Korean journal of parasitology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Simon M MuellerDepartment of Dermatology, University Hospital Basel, Petersgraben 4, 4056, Basel, Switzerland. simon.mueller@usb.ch.
Stefan GysinDepartment of Dermatology, University Hospital Basel, Petersgraben 4, 4056, Basel, Switzerland.
Michael SchweitzerDepartment of Dermatology, University Hospital Basel, Petersgraben 4, 4056, Basel, Switzerland.
Simon SchweglerDepartment of Dermatology, University Hospital Basel, Petersgraben 4, 4056, Basel, Switzerland.
Peter HaeusermannDepartment of Dermatology, University Hospital Basel, Petersgraben 4, 4056, Basel, Switzerland.
Peter ItinDepartment of Dermatology, University Hospital Basel, Petersgraben 4, 4056, Basel, Switzerland.
Thomas BartDepartment of Health, Medical Services, Social Medicine, 4056, Basel, Canton of Basel-City, Switzerland.
Ruth Spieler DenzDepartment of Health, Medical Services, Social Medicine, 4056, Basel, Canton of Basel-City, Switzerland.
Thomas SteffenDepartment of Health, Medical Services, Social Medicine, 4056, Basel, Canton of Basel-City, Switzerland.
Richard KuehlDepartment of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, 4056, Basel, Switzerland.
Andreas F WidmerDepartment of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, 4056, Basel, Switzerland.
Oliver BrandtDepartment of Dermatology, University Hospital Basel, Petersgraben 4, 4056, Basel, Switzerland.
University Hospital of Basel · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInfestations with scabies mites are a global burden affecting individuals of all ages, classes and ethnicities. As poor sanitation and overcrowding favor the transmission of this highly contagious disease, epidemic outbreaks are frequently observed among displaced persons and asylum seekers. Due to the growing influx of refugees during the last years, public health authorities in host countries are frequently confronted with the challenge to treat individuals with diagnosed or suspected scabies promptly and effectively to avoid further spreading of the infestation. This study aimed to establish a straightforward and efficient algorithm for rapid screening and treatment of large numbers of patients with confirmed or suspected scabies infestations.

methodsForty-eight individuals (58% males, mean age 22.4 yrs.) from Syria with suspected scabies infestation were allocated to 3 colour-coded groups: (1) no signs or symptoms of infestation, (2) itch only, and (3) itch and typical skin lesions. Patients were treated with a single (group 1) or two doses of oral ivermectin at an interval of 7 days (group 2), or with a combination of 2 doses of ivermectin plus 2 applications of permethrin ointment at an interval of 7 days (group 3). Follow-ups were performed 4 weeks after initial treatments.

resultsAll individuals with signs and/or symptoms of infestation had improved skin lesion; in 10/11 (90.9%) lesion had completely resolved. All individuals with initial itch only (n = 32) reported improvement of its intensity or complete resolution. None of the patients of group 1 developed itch or skin lesions. The algorithm was reapplied in 4 individuals (8.3%) after 4 weeks and the outbreak was completely controlled after 8 weeks. Colour-coding ensured fast flow of information between health-care providers at the interfaces of the algorithm.

conclusionsOur algorithm proved to be both highly efficient for treatment of large numbers of patients with suspected or diagnosed scabies infestation as well as for prevention of spreading of the disease. Hence, this algorithm is well suited for the management of scabies mass outbreaks.

Indexed as

AlgorithmsAdolescentAdultAgedAnimalsAntiparasitic AgentsDisease OutbreaksFemaleHealth PersonnelHumansInfantIvermectinMaleMiddle AgedPermethrinRefugeesAntiparasitic AgentsIvermectinPermethrinEpidemic outbreakInfection controlIvermectinPermethrinScabies infestation

Identifiers

PMID30819115
PMCPMC6394030
OpenAlexW2923829473

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.