ArticleGenetics, selection, evolution : GSE2019
Effects of heterozygosity on performance of purebred and crossbred pigs.
Article in Genetics, selection, evolution : GSE, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 68 citations in OpenAlex.
- Pooled it
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- Effect of breed composition in genomic prediction using crossbred pig reference population.Journal of animal science and technology · 2025Article
- Multi-Omics Analysis Reveals Dietary Fiber's Impact on Growth, Slaughter Performance, and Gut Microbiome in Durco × Bamei Crossbred Pig.Microorganisms · 2024Article
- Investigating the impact of non-additive genetic effects in the estimation of variance components and genomic predictions for heat tolerance and performance traits in crossbred and purebred pig populations.BMC genomic data · 2023Article
- Multi-breed genomic evaluation for tropical beef cattle when no pedigree information is available.Genetics, selection, evolution : GSE · 2023Article
- VariantscanR: an R-package as a clinical tool for variant filtering of known phenotype-associated variants in domestic animals.BMC bioinformatics · 2023Article
- First large-scale genomic prediction in the honey bee.Heredity · 2023Article
- Optimising clonal performance in sugarcane: leveraging non-additive effects via mate-allocation strategies.Frontiers in plant science · 2023Article
- Performance of crossbred pigs with indigenous and Hampshire inheritance under a smallholder production system in the Eastern Himalayan hill region.Frontiers in genetics · 2023Article
- Impacts of additive, dominance, and inbreeding depression effects on genomic evaluation by combining two SNP chips in Canadian Yorkshire pigs bred in China.Genetics, selection, evolution : GSE · 2022Article
- Genome-wide analysis of hybridization in wild boar populations reveals adaptive introgression from domestic pig.Evolutionary applications · 2022Article
- Evolutionary pressures rendered by animal husbandry practices for avian influenza viruses to adapt to humans.iScience · 2022Review
- Article
- The Association Between Genomic Heterozygosity and Carcass Merit in Cattle.Frontiers in genetics · 2022Article
- Article
- Genome-Wide Assessment of a Korean Composite Pig Breed, Woori-Heukdon.Frontiers in genetics · 2022Article
- Correlations between Antioxidant and Biochemical Parameters of Blood Serum of Duroc Breed Pigs.Animals : an open access journal from MDPI · 2021Article
- Improved genomic prediction of clonal performance in sugarcane by exploiting non-additive genetic effects.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2021Article
- Potential of genomic technologies to improve disease resistance in molluscan aquaculture.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021Review
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundIn pigs, crossbreeding aims at exploiting heterosis, but heterosis is difficult to quantify. Heterozygosity at genetic markers is easier to measure and could potentially be used as an indicator of heterosis. The objective of this study was to investigate the effect of heterozygosity on various maternal and production traits in purebred and crossbred pigs. The proportion of heterozygosity at genetic markers across the genome for each individual was included in the prediction model as a fixed regression across or within breeds.
resultsEstimates of regression coefficients of heterozygosity showed large effects for some traits. For maternal traits, regression coefficient estimates were always in a favourable direction, while for production, meat and slaughter quality traits, they were both favourable and unfavourable. Traits with the largest estimated effects of heterozygosity were total number born, litter weight at 3 weeks, weight at 150 days, and age at 40 kg. Estimates of regression coefficients on heterozygosity differed between breeds. Traits with the largest effect of heterozygosity also showed a significant (P < 0.05) increase in prediction accuracy when heterozygosity was included in the model compared to the model without heterozygosity.
conclusionsFor traits with the largest estimates of regression coefficients on heterozygosity, the inclusion of heterozygosity in the model improved prediction accuracy. Using models that include heterozygosity would result in selecting different animals for breeding, which has the potential to improve genetic gain for these traits. This is most beneficial when crossbreds or several breeds are included in the estimation of breeding values and is relevant to all species, not only pigs. Thus, our results show that including heterozygosity in the model is beneficial for some traits, likely due to dominant gene action.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.