Evidence map›Paper›PMID 30819098›Full record

ArticleBMC cardiovascular disorders2019

Nepal Pioneer Worksite Intervention Study to lower cardio-metabolic risk factors: design and protocol.

Archana Shrestha, Dipesh Tamrakar, Biraj Man Karmacharya, Abha Shrestha, Rajeev Shrestha, Rajendra Dev Bhatta, Prajjwal Pyakurel, Polyna Khudyakov, Vasanti Malik, Josiemer Mattei and 1 more

Registry-linked trialAbstract readClinical Trial Protocol
In one paragraph

Article in BMC cardiovascular disorders, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03447340 (Nepal Pioneer Work-site Intervention Study), which is not on this map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03447340 nacompletednot on this map

Nepal Pioneer Work-site Intervention Study

TypeinterventionalSponsorYale UniversityRan2016 to 2022Enrolled363ConditionsDietary Modification, Diabetes, Hypertension, Health BehaviorArmsCanteen and Behavior intervention, Canteen Only
3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Archana ShresthaDepartment of Epidemiology, Harvard TH Chan School of Public Health, Boston, USA. deararchana@gmail.com.ORCID 0000-0002-4741-090X
Dipesh TamrakarDepartment of Community Medicine, Kathmandu University School of Medical Sciences, Dhulikhel, Nepal.
Biraj Man KarmacharyaDepartment of Community Medicine, Kathmandu University School of Medical Sciences, Dhulikhel, Nepal.
Abha ShresthaDepartment of Community Programs, Dhulikhel Hospital-Kathmandu University Hospital, Dhulikhel, Nepal.
Rajeev ShresthaDepartment of Pharmacology, Kathmandu University School of Medical Sciences, Dhulikhel, Nepal.
Rajendra Dev BhattaDepartment of Biochemistry, Dhulikhel Hospital- Kathmandu University Hospital, Dhulikhel, Nepal.
Prajjwal PyakurelDepartment of Community Medicine, BP Koirala Institute of Health Science, Dharan, Nepal.
Polyna KhudyakovDepartment of Biostatistics, Harvard TH Chan School of Public Health, Boston, USA.
Vasanti MalikDepartment of Nutrition, Harvard TH Chan School of Public Health, Boston, USA.
Josiemer MatteiDepartment of Nutrition, Harvard TH Chan School of Public Health, Boston, USA.
Donna SpiegelmanDepartment of Epidemiology, Harvard TH Chan School of Public Health, Boston, USA.

Funding

Comprehensive Translational Science Analytics Tools for the Global Health AgendaDP1ES025459 · NIEHS · YALE UNIVERSITY · PI SPIEGELMAN, DONNA L · 2014 to 2018
$4.1M
NIEHS NIH HHS DP1 ES025459
6 · The paper itself

Abstract

backgroundTo increase cardiovascular disease prevention efforts, worksite interventions can promote healthy food choices, facilitate health education, increase physical activity and provide social support. This pioneer study will measure the effectiveness of a cafeteria and a behavioral intervention on cardio-metabolic risk in a worksite in Nepal.

methodsThe Nepal Pioneer Worksite Intervention Study is a two-step intervention study conducted in Dhulikhel Hospital in eastern Nepal. In the first step, we will assess the effectiveness of a 6-month cafeteria intervention on cardio-metabolic risk using a pre-post design. In the second step, we will conduct a 6-month, open-masked, two-arm randomized trial by allocating half of the participants to an individual behavioral intervention based on the 'diabetes prevention program' for the prevention of cardio-metabolic risk. We will recruit 366 full time employees with elevated blood pressure, fasting blood sugar, or glycosylated haemoglobin (HbA1c). At baseline, we will measure their demographic variables, lifestyle factors, anthropometry, fasting blood sugar, HbA1c,and lipid profiles. We will measure cardio-metabolic outcomes at 6 months, 12 months, and 18 months. At 12 months, we will compare the proportion of participants who have attained two or more cardio-metabolic risk factor reduction goals (HbA1 DISCUSSION: This pioneer study will estimate the effect of environmental-level changes on lowering cardio-metabolic risks; and added benefit of an individual-level dietary intervention. If the study demonstrates a significant effect, a scaled up approach could produce an important reduction in cardiovascular disease burden through environmental and individual level prevention programs in Nepal and similar worksites worldwide.

trial registrationThe trial was retrospectively registered on clincaltrials.gov (Identification Member: NCT03447340 ; Date of Registration: February 27, 2018).

Indexed as

Diet, HealthyFood ServicesOccupational Health ServicesPatient Education as TopicRisk Reduction BehaviorCardiovascular DiseasesExerciseFemaleHealth Knowledge, Attitudes, PracticeHumansMaleMetabolic SyndromeNepalProtective FactorsRandomized Controlled Trials as TopicRisk FactorsCardio-metabolic riskDiabetesHypertensionNepalWorksite

Identifiers

PMID30819098
PMCPMC6393979

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.