Evidence map›Paper›PMID 30818909›Full record

ArticleZhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology2019

[Considerations of using oral nucleos(t)ide analogues to interrupt mother-to-child transmission in HBV carrier pregnant woman with high viral load].

Y Ding, Q J Sheng, X G Dou

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Y DingDepartment. of Infectious Disease, Shengjing Hospital of China Medical University, Shenyang 110022, China.
Q J Sheng
X G Dou
China Medical University · CN

Funding

Liaoning Provincial Local Professional Technology Innovation Platform Construction Project 2016007013Liaoning Provincial Natural Science Foundation 2014021007Medical Science Study Foundation YWJKJJHKYJJ-B181004"Thirteenth Five-Year Plan" Major National Science and Technology Major Projects 2017ZX10201201, 2017ZX10202202
6 · The paper itself

Abstract

The main transmission route of chronic hepatitis B virus infection is mother-to-child transmission of hepatitis B virus and the main cause of combined immune prophylaxis failure in neonates at the end of pregnancy is high viral load. Moreover, oral administration of nucleos(t)ide analogues (NAs) during the second and third trimesters of pregnancy can significantly reduce or even completely block mother-to-child transmission of HBV. This article focuses on the necessity and feasibility of oral NAs antiviral therapy for HBV carrier pregnant woman with high viral load, and the issues commences at the time of medication and viral load thresholds.

Indexed as

Antiviral AgentsDNA, ViralFemaleHepatitis B, ChronicHepatitis B virusHumansInfant, NewbornInfectious Disease Transmission, VerticalNucleosidesNucleotidesPregnancyPregnancy Complications, InfectiousViral LoadAntiviral AgentsDNA, ViralNucleosidesNucleotidesHepatitis B virusMother-to-child transmissionNucleos(t)ide analoguesTherapy

Identifiers

PMID30818909
PMCPMC12769032
OpenAlexW2990670040

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.