Trial reportNutrients2019
Effect of Iron Supplementation on the Modulation of Iron Metabolism, Muscle Damage Biomarkers and Cortisol in Professional Cyclists.
Trial report in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06942208 (Iron Revisited), which is not on this map. Cited by 20 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Iron Revisited: Alternate-Day Oral Iron Supplementation in Endurance, Intermittent, and Power/Strength Athletes
Who cites it
20 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- The relationship between hemoglobin andPloS one · 2023Pooled it
- Effects of Vitamin D in Post-Exercise Muscle Recovery. A Systematic Review and Meta-Analysis.Nutrients · 2021Pooled it
- Pooled it
- Pooled it
- Trial
- Association of Stress and Inflammatory Diseases with Serum Ferritin and Iron Concentrations in Neonatal Calves.Animals : an open access journal from MDPI · 2025Article
- Effect of Off-Season Iron Supplementation on Aerobic Capacity of Female Handball Player: A Randomized, Double-Blinded, Placebo-Controlled Study.Current developments in nutrition · 2024Article
- Iron Status and Physical Performance in Athletes.Life (Basel, Switzerland) · 2023Review
- Effects of L-Carnitine Intake on Exercise-Induced Muscle Damage and Oxidative Stress: A Narrative Scoping Review.Nutrients · 2023Article
- Influence of iron supplementation on fatigue, mood states and sweating profiles of healthy non-anemic athletes during a training exercise: A double-blind, randomized, placebo-controlled, parallel-group study.Contemporary clinical trials communications · 2023Article
- The role and regulation mechanism of Chinese traditional fitness exercises on the bone and cartilage tissue in patients with osteoporosis: A narrative review.Frontiers in physiology · 2023Review
- Influences of Vitamin D and Iron Status on Skeletal Muscle Health: A Narrative Review.Nutrients · 2022Review
- Effects of Eccentric vs. Concentric Sports on Blood Muscular Damage Markers in Male Professional Players.Biology · 2022Article
- Effects of 4-Week Tangeretin Supplementation on Cortisol Stress Response Induced by High-Intensity Resistance Exercise: A Randomized Controlled Trial.Frontiers in physiology · 2022Article
- Changes of Serum Ferritin, Hemoglobin, and Serum Iron (SI) and Treatment Effect of Iron Proteinsuccinylate Oral Solution Combined with Vitamin A and D Drops on Children with Nutritional Iron Deficiency Anemia.BioMed research international · 2022Article
- Adverse effects of iron deficiency anemia on pregnancy outcome and offspring development and intervention of three iron supplements.Scientific reports · 2021Article
- Effects of Curcumin Supplementation on Inflammatory Markers, Muscle Damage, and Sports Performance during Acute Physical Exercise in Sedentary Individuals.Oxidative medicine and cellular longevity · 2021Review
- Iron and Physical Activity: Bioavailability Enhancers, Properties of Black Pepper (BioperineNutrients · 2020Review
- Article
- Impact of Magnesium Supplementation in Muscle Damage of Professional Cyclists Competing in a Stage Race.Nutrients · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe intense efforts made during 3-week stage races may reduce iron metabolism and hematological parameters. These efforts may increase the levels of circulating muscle damage markers and some hormones. All of these physiological changes may have negative consequences not only for the performance of athletes but also for their health. The main aim of this study was to evaluate the effects of supplementation with 80 mg/day of iron on haematological parameters, serum cortisol and biochemical muscle indicators on elite male cyclists during the 3-week stage race the
methodsEighteen elite male cyclists from two teams were randomly assigned to one of two groups: (1) control group (CG,
resultsSignificant differences were observed between groups throughout the study in the group-by-time interaction and changes in serum iron (GC: -8.93 ± 10.35% vs. ITG: 0.60 ± 8.64%;
conclusionsOral iron supplementation with 80 mg/day iron (800 mg of iron protein succinylate) effectively prevented a decline in haematological parameters (serum iron, ferritin, haemoglobin and haematocrit) and maintained optimal levels of recovery in elite cyclists during the
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.