Evidence map›Paper›PMID 30818381›Full record

ArticlePloS one2019

Associations between spouses' oxytocin receptor gene polymorphism, attachment security, and marital satisfaction.

Joan K Monin, Selin O Goktas, Trace Kershaw, Andrew DeWan

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
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  5. Article
  6. Brain serotonin, oxytocin, and their interaction: Relevance for eating disorders.Journal of psychopharmacology (Oxford, England) · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Joan K MoninSocial and Behavioral Sciences, Yale School of Public Health, New Haven, CT, United States of America.ORCID 0000-0002-1729-0230
Selin O GoktasPsychiatry, Yale School of Medicine, New Haven, CT, United States of America.
Trace KershawSocial and Behavioral Sciences, Yale School of Public Health, New Haven, CT, United States of America.
Andrew DeWanChronic Disease Epidemiology, Yale School of Public Health, New Haven, CT, United States of America.
Yale University · US

Funding

Yale Study Support Suite (YES3): Dashboard and Web Portal Software Supporting Research Workflow through integrated, customizable REDCap External ModulesP30AG021342 · NIA · YALE UNIVERSITY · PI Albert C Shaw · 2002 to 2026
$37.9M
Chronic Conditions and Mutuality of Care in Late Life Marriage:A Multi-method AppK01AG042450 · NIA · YALE UNIVERSITY · PI MONIN, JOAN E. · 2013 to 2017
$634k
NIA NIH HHS K01 AG042450NIA NIH HHS P30 AG021342
6 · The paper itself

Abstract

OXTR rs53576, a polymorphism on the oxytocin receptor gene, has previously been linked to individual differences in social behaviors. That is, individuals with the GG genotype show greater empathy, sociability, and emotional stability. In the context of close relationships, such psychological resources are associated with better relationship outcomes. However, no studies to our knowledge have examined associations between spouses' OXTR polymorphisms, attachment security, and marital satisfaction. In the current study, 178 married couples (N = 356; ages 37-90) completed self-report measures of attachment security and marital satisfaction and provided saliva samples for genotyping. Results from Actor Partner Interdependence Models showed that individuals who had the GG genotype (actor effect) or had a spouse with the GG genotype (partner effect) reported greater marital satisfaction than individuals with AA or AG genotypes. Furthermore, greater attachment security mediated associations between GG genotype and marital satisfaction.

Indexed as

Polymorphism, Single NucleotideAdultAgedAged, 80 and overEmotionsFemaleGenetic MarkersGenotypeHumansMaleMarriageMiddle AgedModels, GeneticModels, PsychologicalObject AttachmentPersonal SatisfactionGenetic MarkersOXTR protein, humanReceptors, Oxytocin

Identifiers

PMID30818381
PMCPMC6395040
OpenAlexW2916577850

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.