Evidence map›Paper›PMID 30817619›Full record

ArticleMedicine2019

TCM therapies combined with chemotherapy for preventing recurrence and metastasis in postoperative II to IIIA NSCLC: A protocol for a systematic review and meta-analysis.

Shuntai Chen, Zhenhua Zhang, Xiwen Zhang, Runzhi Qi, Juling Jiang, Xing Zhang, Yupeng Xi, Rui Liu, Qiujun Guo, Honggang Zheng and 1 more

Abstract read
In one paragraph

Article in Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Shuntai ChenGraduate School, Beijing University of Chinese Medicine.
Zhenhua ZhangGraduate School, Beijing University of Chinese Medicine.
Xiwen ZhangDepartment of Oncology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Runzhi QiDepartment of Oncology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Juling JiangDepartment of Oncology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Xing ZhangGraduate School, Beijing University of Chinese Medicine.
Yupeng XiGraduate School, Beijing University of Chinese Medicine.
Rui LiuDepartment of Oncology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Qiujun GuoDepartment of Oncology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Honggang ZhengDepartment of Oncology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Baojin HuaDepartment of Oncology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTraditional Chinese Medicine (TCM) therapies have been combined with chemotherapy for preventing Recurrence and metastasis in postoperative II to IIIA non-small-cell lung cancer (NSCLC) and the associated better disease-free survival (DFS), but its effects remain elusive. The purpose of this review is to assess the efficacy of TCM therapies as a treatment for postoperative II to IIIA NSCLC. METHODS AND ANALYSIS: Seventh databases will be searched for relevant studies from inception to the present date. We will include randomized controlled trials assessing TCM therapies combined with chemotherapy for preventing Recurrence and metastasis in postoperative II to IIIA NSCLC. The methodological qualities, including the risk of bias, will be evaluated using the Cochrane risk of bias assessment tool, while confidence in the cumulative evidence will be evaluated using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach. ETHICS AND DISSEMINATION: Ethical approval is not required, as this study is based on the review of published research. This review will be published in a peer-reviewed journal and disseminated both electronically and in print. PROSPERO REGISTRATION NUMBER: The protocol for this systematic review has been registered on PROSPERO under the number CRD42019116594.

Indexed as

Research DesignAntineoplastic AgentsCarcinoma, Non-Small-Cell LungDisease-Free SurvivalHumansLung NeoplasmsMedicine, Chinese TraditionalMeta-Analysis as TopicNeoplasm MetastasisNeoplasm Recurrence, LocalNeoplasm StagingSystematic Reviews as TopicAntineoplastic Agents

Identifiers

PMID30817619
PMCPMC6831319

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.