Evidence map›Paper›PMID 30817614›Full record

SynthesisMedicine2019

Diagnostic value of cadmium-zinc-telluride myocardial perfusion imaging versus coronary angiography in coronary artery disease: A PRISMA-compliant meta-analysis.

Yi-Qing Zhang, Yu-Feng Jiang, Lu Hong, Min Chen, Nan-Nan Zhang, Hua-Jia Yang, Ya-Feng Zhou

Registry-linked trialAbstract readMeta-AnalysisReview
In one paragraph

Synthesis in Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07708805 (Quantitative Myocardial Perfusion Imaging Assessment by SPECT/CT), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07708805 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Quantitative Myocardial Perfusion Imaging Assessment by SPECT/CT: Evaluation of Standardized Uptake Value (SUV) and Correlation With Myocardial Flow Reserve (MFR) Assessed by PET/CT

TypeinterventionalSponsorCentre Hospitalier Régional d'OrléansRan2026 to 2027Enrolled30ConditionsCoronary Artery Disease, Chronic Coronary SyndromeArmsstress SPECT/CT, rest SPECT/CT
3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Can myocardial perfusion imaging predict outcome in patients with angina and ischemia but no obstructive coronary artery disease (INOCA)?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
  5. Review
  6. The value of coronary CTA in the diagnosis of coronary artery disease.American journal of translational research · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yi-Qing ZhangDepartment of Cardiology, the First Affiliated Hospital of Soochow University, Suzhou City, Jiangsu Province, P. R. China.
Yu-Feng Jiang
Lu Hong
Min Chen
Nan-Nan Zhang
Hua-Jia Yang
Ya-Feng Zhou

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRapid progress has been made in research of cadmium-zinc-telluride (CZT) technology in the last few years, which might serve as a new method to diagnose coronary artery disease. However, compared with coronary angiography, the diagnostic value of CZT is still controversial. We aimed to evaluate diagnosis value of coronary angiography versus CZT in coronary artery disease.

methodsWe searched the database for eligible researches associated with CZT- myocardial perfusion imaging (MPI) and invasive coronary angiography, extracted the relevant data, and rigorously screened it according to the inclusion and exclusion criteria. The accuracy indicators included sensitivity, specificity, accuracy, positive and negative likelihood ratios.

resultsAccording to the inclusion and exclusion criteria, we finally found 20 studies containing 2350 patients in this search. Pooled results showed that sensitivity of CZT-MPI was 0.84% and 95% confidence interval (95% CI): 0.78 to 0.89, specificity was 0.72, 95% CI (0.62-0.76), the specificity was lower apparently. The positive likelihood ratio was 3.0, 95% CI (2.4-3.8), the negative likelihood ratio was 0.22, 95% CI (0.16-0.31), diagnostic odds ratio was 14, 95% CI (7.84-17.42).

conclusionThis meta-analysis showed that CZT-MPI had satisfactory sensitivity and specificity for diagnosing coronary artery disease. Larger studies are required for further evaluation.

Indexed as

Coronary AngiographyCoronary Artery DiseaseHumansMyocardial Perfusion ImagingSensitivity and Specificity

Identifiers

PMID30817614
PMCPMC6831125

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.