Evidence map›Paper›PMID 30817284›Full record

ArticleCanadian Urological Association journal = Journal de l'Association des urologues du Canada2019

The My-T study: Patient satisfaction and preference comparing topical and nasal testosterone therapies.

Jay Lee, Gerald Brock, Jack Barkin, Nathan Bryson, Matthew A Gronski, Ross Ormsby

Abstract read
In one paragraph

Article in Canadian Urological Association journal = Journal de l'Association des urologues du Canada, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Study shows patients have a positive perception of testosterone nasal gel.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2019
    Article
  7. Efficacy of Nasal Testosterone Gel (NatestoJournal of the Endocrine Society · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jay LeeDepartment of Surgery, Division of Urology, University of Calgary, Calgary, AB, Canada.
Gerald BrockDepartment of Surgery, Division of Urology, St. Joseph's Health Care, London, ON, Canada.
Jack BarkinDepartment of Surgery, University of Toronto, Humber River Regional Hospital, Toronto, ON, Canada.
Nathan BrysonAcerus Pharmaceuticals Corporation, Mississauga, ON, Canada.
Matthew A GronskiAcerus Pharmaceuticals Corporation, Mississauga, ON, Canada.
Ross OrmsbyAcerus Pharmaceuticals Corporation, Mississauga, ON, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionNatesto

methodsThe study enrolled 24 TTh-naive (TThN) and 93 TTh-experienced (TThE) hypogonadal men. Treatment lasted up to 120 days, with titration at day 90 to determine the most appropriate dose for restoration of testosterone levels (11 mg bid or tid). Patient satisfaction and symptom changes were measured at days 0, 30, 60, 90, and 120. The PPU Questionnaire was performed at study entry and study completion.

resultsSymptoms improved from baseline (30.6) to day 90 (35.1) (p<0.0001; +15%), consistent with testosterone replacement. TNG increased scores for effectiveness (+20%), convenience (+30%), and global satisfaction (+3%) as compared to their previous topical TTh. TThE patients reported ease of use, convenience, efficacy/effectiveness, and travel friendliness as "likes" of TNG therapy. Overall, 67.2% of patients agreed or strongly agreed that they preferred TNG over topical TTh and 59% sought a prescription to continue treatment with TNG.

conclusionsPatients switching from topical TTh to TNG reported significant improvements in symptoms and patient satisfaction compared to their previous topical TTh. Patients also reported a significant improvement in convenience with TNG despite two to three times daily application. Preference, satisfaction, and convenience may translate to better treatment compliance.

Identifiers

PMID30817284
PMCPMC6892698

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.