ArticleJournal of clinical oncology : official journal of the American Society of Clinical Oncology2019
Trends in Opioid Use Among Older Survivors of Colorectal, Lung, and Breast Cancers.
Article in Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 39 papers.
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Who cites it
39 citing papers in PubMed.
- Article
- Opioid prescribing to older cancer survivors: a retrospective claims-based characterization of prescriber specialties.Journal of cancer survivorship : research and practice · 2025Article
- Opioid prescription and usage disparities among Puerto Rican breast cancer survivors: findings from the Puerto Rico central cancer registry-health insurance linkage database (PRCCR-HILD).Cancer causes & control : CCC · 2025Article
- Opioid prescribing trends and pain scores among adult patients with cancer in a large health system.Cancer · 2025Article
- Comparative Effectiveness of Opioids and Opioid Substitutes on Pain and Health Related Quality of Life Among Cancer Survivors.Cancer medicine · 2025Article
- Prescription opioid use and opioid use disorder among older adults with HIV in the USA from 2008 to 2021: a retrospective repeated cross-sectional study.The Lancet. Primary care · 2025Article
- Article
- Persistent prescription opioid use and all-cause mortality following the first-year breast cancer survivorship.JNCI cancer spectrum · 2025Article
- Opioid use and adverse health effects in breast cancer survivors.The oncologist · 2025Article
- Article
- Cannabis and opioid perceptions, co-use, and substitution among patients across 4 NCI-Designated Cancer Centers.Journal of the National Cancer Institute. Monographs · 2024Article
- Opioid tapering in older cancer survivors does not increase psychiatric or drug hospitalization rates.Journal of the National Cancer Institute · 2024Article
- Association between trajectories of prescription opioid use and risk of opioid use disorder and overdose among US nonmetastatic breast cancer survivors.Breast cancer research and treatment · 2024Article
- Prevalence of abnormal urine drug tests during COVID-19 pandemic in the cancer patient population: retrospective study.Pain management · 2024Article
- Article
- Trends in new and persistent opioid use in older adults with and without cancer.Journal of the National Cancer Institute · 2024Article
- "It Is So Easy For Them to Dismiss": A Phenomenological Study of Cancer Survivors With Chronic Cancer-Related Pain.Journal of palliative medicine · 2023Article
- Long-term opioid therapy trajectories and overdose in patients with and without cancer.BMJ oncology · 2023Article
- Polymorphisms inGenes · 2022Article
- Trends in the Use of Opioids vs Nonpharmacologic Treatments in Adults With Pain, 2011-2019.JAMA network open · 2022Article
Corrections and comments
- Erratum issuedErratum.2019
Authors and funding
7 authors.
Funding
Abstract
purposeCancer survivors may be at increased risk for opioid-related harms. Trends in opioid use over time since diagnosis are unknown.
methodsUsing data from SEER and Medicare, we conducted multilevel logistic regression analyses to compare chronic opioid use (≥ 90 consecutive days) among opioid-naïve survivors of colorectal, lung, and breast cancers diagnosed from 2008 to 2013 and matched with noncancer controls. Among cases and controls with chronic use, we compared rates of high-dose opioid use (average ≥ 90 morphine milligram equivalents daily).
resultsWe included 46,789 survivors and 138,136 noncancer controls. In the first year after the index date (survivor's diagnosis date), chronic use among colorectal and lung cancer survivors exceeded chronic use among controls (colorectal cancer: odds ratio, 1.34; 95% CI, 1.22 to 1.47; lung cancer: odds ratio, 2.55; 95% CI, 2.34 to 2.77). Differences in chronic use between survivors and controls declined each year after the index date. Chronic use among breast cancer survivors was less than that of controls each year after the index date. Survivors with chronic use were more likely to have a high daily dose than controls with chronic use in the first 3 to 5 years.
conclusionAmong three large populations of older cancer survivors, chronic opioid use varied by cancer. However, by 6 years after diagnosis, survivors were no longer more likely to be chronic users than controls. Strategies for appropriate pain management during and after cancer treatment should take into account the risks associated with chronic high-dose opioid use.
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