Evidence map›Paper›PMID 30817247›Full record

ReviewMolecular biology of the cell2019

Life is sweet: the cell biology of glycoconjugates.

Alex C Broussard, Michael Boyce

Open access · greenAbstract readReview
In one paragraph

Review in Molecular biology of the cell, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. What is the Sugar Code?Chembiochem : a European journal of chemical biology · 2022
    Review
  13. Glycobiology of Cancer: Sugar Drives the Show.Medicines (Basel, Switzerland) · 2022
    Article
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Alex C BroussardDepartment of Biochemistry and Program in Cell and Molecular Biology, Duke University School of Medicine, Durham, NC 27710.
Michael BoyceDepartment of Biochemistry and Program in Cell and Molecular Biology, Duke University School of Medicine, Durham, NC 27710.
Duke University · US

Funding

Cell signaling through O-GlcNAc reader proteinsR01GM118847 · NIGMS · DUKE UNIVERSITY · PI BOYCE, MICHAEL S · 2016 to 2025
$2.8M
Control of COPII vesicle trafficking by intracellular protein glycosylationR01GM117473 · NIGMS · DUKE UNIVERSITY · PI BOYCE, MICHAEL S · 2017 to 2025
$2.6M
Metabolic regulation of KLHL proteins through O-glycosylationR01NS111588 · NINDS · DUKE UNIVERSITY · PI BOYCE, MICHAEL S, CHI, JEN-TSAN ASHLEY · 2019 to 2022
$2.1M
NIGMS NIH HHS R01 GM117473NIGMS NIH HHS R01 GM118847NINDS NIH HHS R01 NS111588
6 · The paper itself

Abstract

Cells are dazzling in their diversity, both within and across organisms. And yet, throughout this variety runs at least one common thread: sugars. All cells on Earth, in all domains of life, are literally covered in glycans, a term referring to the carbohydrate portion of glycoproteins and glycolipids. In spite of (or, perhaps, because of) their tremendous structural and functional complexity, glycans have historically been underexplored compared with other areas of cell biology. Recently, however, advances in experimental systems and analytical methods have ushered in a renaissance in glycobiology, the study of the biosynthesis, structures, interactions, functions, and evolution of glycans. Today, glycobiology is poised to make major new contributions to cell biology and become more fully integrated into our understanding of cell and organismal physiology.

Indexed as

AnimalsGlycoconjugatesHumansLigandsPolysaccharidesReceptors, Cell SurfaceSignal TransductionSpecies SpecificityGlycoconjugatesLigandsPolysaccharidesReceptors, Cell Surface

Identifiers

PMID30817247
PMCPMC6589694
OpenAlexW2918598920

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.